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  • Ying-xin Qi, Jun Jiang, +8 authors Zong-lai Jiang
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 2011 (First Publication: 1 February 2011)
  • Shear stress, especially low shear stress (LowSS), plays an important role in vascular remodeling during atherosclerosis. Endothelial cells (ECs), which are directly exposed to shear stress, convertContinue Reading
  • Xiaohua Jiang, Benjamin Chun-yu Wong, +5 authors S. Katherine Lam
  • Biology, Medicine
  • Oncogene
  • 2001 (First Publication: 1 November 2001)
  • Triptolide, a major component in the extract of Chinese herbal plant Tripterygium wilfordii Hook f (TWHf), has potential anti-neoplastic effect. In the present study we investigated the potentialContinue Reading
  • Ya-qiu Long, Xiaohua Jiang, +4 authors Nouri Neamati
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 2004 (First Publication: 1 May 2004)
  • Discovery of diketoacid-containing compounds as HIV-1 integrase (IN) inhibitors played a major role in validating this enzyme as an important target for the development of therapeutics against HIVContinue Reading
  • Xin Wang, Jun-ling Gao, +7 authors Jian-Zhong Cui
  • Medicine, Biology
  • International journal of molecular medicine
  • 2018 (First Publication: 24 November 2017)
  • Pulmonary fibrosis (PF) is a chronic lung disease. The transforming growth factor-β1 (TGF-β1)/Smad3 signaling pathway plays an important role in the pathogenesis of pulmonary fibrosis. BoneContinue Reading
  • Yan Feng, Ying Cui, +7 authors Jian-Zhong Cui
  • Medicine
  • International journal of molecular medicine
  • 2016 (First Publication: 19 February 2016)
  • Previous research has demonstrated that traumatic brain injury (TBI) activates autophagy and a neuroinflammatory cascade that contributes to substantial neuronal damage and behavioral impairment, andContinue Reading