Xiaohu Huang

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In the heart, autophagy has been implicated in cardioprotection and ischemia-reperfusion tolerance, and the dysregulation of autophagy is associated with the development of heart failure. Mitochondrial dynamic proteins are profoundly involved in autophagic processes, especially the initiation and formation of autophagosomes, but it is not clear whether they(More)
Mitochondrial fusion is a highly coordinated process that mixes and unifies the mitochondrial compartment for normal mitochondrial functions and mitochondrial DNA inheritance. Dysregulated mitochondrial fusion causes mitochondrial fragmentation, abnormal mitochondrial physiology and inheritance, and has been causally linked with a number of neuronal(More)
BACKGROUND AND PURPOSE High-salt diet induces cardiac remodelling and leads to heart failure, which is closely related to cardiac mitochondrial dysfunction. Transient receptor potential (TRP) channels are implicated in the pathogenesis of cardiac dysfunction. We investigated whether activation of TRP vanilloid (subtype 1) (TRPV1) channels by dietary(More)
Thermoelectric material Bi2Te3 nanowire arrays have been successfully prepared by pulsed electrochemical deposition into the nanochannels of porous anodic alumina membranes. X-ray diffraction analyses show that the as-synthesized nanowires have a highly preferential orientation. Scanning electron microscopy, transmission electron microscopy, and(More)
Mitochondria in many types of cells are dynamically interconnected through constant fusion and fission, allowing for exchange of mitochondrial contents and repair of damaged mitochondria. However, constrained by the myofibril lattice, the ∼6,000 mitochondria in the adult mammalian cardiomyocyte display little motility, and it is unclear how, if at all, they(More)
It is now accepted that the physical forces in ultrasonic cleaning are due to strongly pulsating bubbles driven by the sound field. Here we have a detailed look at bubble induced cleaning flow by analyzing the transport of an individual particle near an expanding and collapsing bubble. The induced particulate transport is compared with a force balance(More)
Multiwalled carbon nanotubes (MWCNT) are exposed to a transient and strong liquid jet flow created by a pair of differently sized laser-induced cavitation bubbles. The position and size of the bubbles are controlled with a spatial light modulator within a 15 microm thick liquid gap. Depending on the tube's position with respect to this jet flow, rotation,(More)
The thermal properties of single-crystalline Bi nanowire arrays with different orientations and diameters were studied by differential scanning calorimeter and in situ high-temperature X-ray diffraction. Bi nanowires were fabricated by a pulsed electrodeposition technique within the porous anodic alumina membrane. The relationships between the orientation(More)
The flow induced by a single laser-induced cavitation bubble is used to manipulate individual Co nanowires. The short-lived (<20 μs) bubble with a maximum size of 45 μm is created in an aqueous solution with a laser pulse. Translation, rotation, and radial motion of the nanowire can be selectively achieved by varying the initial distance and orientation of(More)
Semiconductor ZnTe nanowire arrays have been synthesized by the pulsed electrochemical deposition from aqueous solutions into porous anodic alumina membranes. X-ray diffraction analyses show that the as-synthesized nanowires have a highly preferential orientation. Scanning electron microscopy, transmission electron microscopy, and high-resolution(More)