Xiaohong Dong

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TGF-β1 plays an important role on podocyte injury and glomerular diseases, while the underlying molecular mechanisms are still elusive. Here, the potential role of the ion channel TRPC6 and the proximal signaling was explored in TGF-β1-treated mouse podocyte. Our results showed that TGF-β1 significantly increased podocyte apoptosis and induced obvious(More)
It has been demonstrated that nephrin inactivation plays a critical role in Angiotensin II (AngII)-induced podocyte damage both in in vitro and in vivo, but the underlying molecular mechanisms are still unclear. Recently, c-maf inducing protein (c-mip) has been identified as a key component in the molecular pathogenesis of acquired podocyte diseases. In(More)
OBJECTIVE The aim of this meta-analysis and systematic review is to evaluate the safety and efficacy of Chinese herbal medicine (CHM) for chronic prostatitis (CP) associated with damp-heat and blood-stasis syndromes. METHODS An electronic search of 13 databases up to May 2016 was screened to identify randomized controlled trials comparing the safety and(More)
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