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  • Young E. Whang, Xiaogiang Wu, +6 authors Charles L Sawyers
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1998 (First Published: 28 April 1998)
  • The recently identified PTEN/MMAC1 gene is a candidate tumor suppressor implicated in multiple tumor types based on mutations or homozygous deletions of the gene in certain human cancers. No studiesContinue Reading
  • Lei Sun, Nyla A. Heerema, +6 authors Fatih M. Uckun
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1999 (First Published: 19 January 1999)
  • Ikaros, a zinc finger-containing DNA-binding protein, is required for normal lymphocyte development, and germline mutant mice that express only non-DNA binding dominant-negative "leukemogenic" IkarosContinue Reading