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Inhibitions of epithelial to mesenchymal transition and cancer stem cells‐like properties are involved in miR‐148a‐mediated anti‐metastasis of hepatocellular carcinoma
TLDR
The results suggest that miR‐148a inhibits the metastasis of HCCs by blocking EMT and CSCs‐like properties through effects on the Wnt signaling pathway.
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Combination Therapy of Radiofrequency Ablation and Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma
TLDR
Main tumor size, number of tumors, and treatment modality were demonstrated to be important factors associated with 3-year intrahepatic recurrence-free survival probability and overall survival probability by univariate and multivariate analyses.
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MiR‐24‐3p enhances cell growth in hepatocellular carcinoma by targeting metallothionein 1M
TLDR
Results indicated that miR‐24‐3p plays an important role in the initiation and progression of HCC by targeting metallothionein 1M, and the miR-24‐ 3p/metallothionin 1m pathway may contribute to the development of novel therapeutic strategies for HCC in the future.
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Strategy for discriminating cholesterol and premalignancy in polypoid lesions of the gallbladder: a single‐centre, retrospective cohort study
The present study aimed to assess the risk factors of cholesterol and premalignancy in polypoid lesions of the gallbladder (PLGs) and to establish an appropriate treatment strategy.
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Modularized laparoscopic regional en bloc mesogastrium excision (rEME) based on membrane anatomy for distal gastric cancer
TLDR
Laparoscopic radical gastrectomy plus modularized rEME based on the membrane anatomy is a safe and feasible procedure for distal gastric cancer.
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Rapid diagnosis of lung cancer and glioma based on serum Raman spectroscopy combined with deep learning
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Natural product pectolinarigenin inhibits proliferation, induces apoptosis, and causes G2/M phase arrest of HCC via PI3K/AKT/mTOR/ERK signaling pathway
TLDR
Pectolinarigenin could suppress the viability and motility and cause apoptosis and G2/M phase arrest in HCC cell lines by inhibiting the PI3K/AKT/mTOR/ERK signaling pathway, which might be an appealing potential therapeutic agent for HCC treatment.
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Elevated expression of neuropilin-2 associated with unfavorable prognosis in hepatocellular carcinoma
TLDR
It is suggested that NRP2 expression was considered as an independent factor for the prediction of unfavorable prognosis in HCC patients, and it is believed that N RP2 could serve as a biomarker of poor prognosis and a novel target in treating HCC tumors.
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915-MHz microwave-assisted laparoscopic hepatectomy: a new technique for liver resection
TLDR
915-MHz microwave-assisted LH was found to be safe and efficient and shorter length of postoperative hospital stay in the microwave group, compared with the control group.
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Knockdown of Gli1 by small-interfering RNA enhances the effects of BCNU on the proliferation and apoptosis of glioma U251 cells.
TLDR
Combined treatment with siRNA-Gli1 and BCNU significantly inhibits the proliferation and promotes the apoptosis of glioma U251 cells, and enhances the inhibition of cell cycles, but does not down-regulate the expression of cell cycle protein cyclin D1.
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