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  • Jing Du, Xiaofei Chen, +7 authors Chun Yang
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2011 (First Publication: 7 June 2011)
  • The mechanism by which ECM elasticity induces lineage specification of stem cells has not been clearly understood. Integrins are well-documented mechanosensors that are positioned at the beginning ofContinue Reading
    Introduction: Enhancer of zeste homologue 2 (EZH2) is a critical enzymatic subunit of the polycomb repressive complex 2 (PRC2) which trimethylates histone H3 (H3K27) to mediate gene repression. EZH2Continue Reading