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—Calibration of the spatial sensitivity functions of coil arrays is a crucial element in parallel magnetic resonance imaging (pMRI). The self-calibrating technique for sensitivity extraction has complemented the common calibration technique that uses a separate pre-scan. In order to improve the accuracy of sensitivity estimate from small number of(More)
Over the past two decades, a striking increase in the number of people with metabolic syndrome (MS) has taken place worldwide. With the elevated risk of not only diabetes but also cardiovascular morbidity and mortality, there is urgent need for strategies to prevent this emerging global epidemic. The present study was undertaken to investigate the effects(More)
BACKGROUND MicroRNAs (miRNAs) are short, non-coding RNAs that negatively regulate target genes. A single nucleotide polymorphism (SNP) in a miRNA sequence may alter miRNA expression and/or maturation, which was proposed to associate with the development and progression of cancer. The rs895819 polymorphism, located in the terminal loop of pre-miR-27a, has(More)
Beta cell mass and function are decreased to varying degrees in diabetes. Islet cell replacement or regenerative therapy may offer great therapeutic promise to people with diabetes. In addition to primary pancreatic β cells, recent studies on regeneration of functional insulin producing cells (IPCs) revealed that several alternative cell sources, including(More)
Hepatocellular carcinoma (HCC) is the sixth common cancer and the third common cause of cancer mortality worldwide. However, the exact molecular mechanism of HCC remains uncertain. Many enzymes are involved in one-carbon metabolism (OCM), and single nucleotide polymorphisms (SNPs) in the corresponding genes may play a role in liver carcinogenesis. In this(More)
—Sleep apnea (SA) is accompanied by a characteristic cyclic variation in heart rate in the waveform of the electrocardiogram (ECG). If sleep apnea were able to be diagnosed with ECG only, it could revolutionalise the diagnosis of sleep apnea by allowing patient's to be diagnosed within their own homes. The most informative feature of ECG recordings is a low(More)
A Kernel Spectral Angle Mapper (KSAM) algorithm is proposed to deal better with the nonlinear classification problem of the remote sensing image. The so-called KSAM algorithm is achieved by introducing the kernel method into the standard Spectral Angle Mapper (SAM) algorithm. Experimental results indicate that the classification accuracy of the KSAM(More)
A novel class of transcripts, long non-coding RNAs (lncRNAs), has recently emerged as a key player in several biological processes, and important roles for these molecules have been reported in a number of complex human diseases, such as autoimmune diseases, neurological disorders, and various cancers. However, the aberrant lncRNAs implicated in myasthenia(More)