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Based on intravascular ultrasound (IVUS) video images, a novel motion estimation method combining the genetic algorithm-based optical flow method and a step-by-step and sum strategy has been developed to estimate the displacement and strain distributions on the scan cross sections of the arteries. And then, real elasticity distributions were reconstructed(More)
OBJECTIVE To identify systemic sclerosis (SSc) susceptibility loci via a genome-wide association study. METHODS A genome-wide association study was performed in 137 patients with SSc and 564 controls from Korea using the Affymetrix Human SNP Array 5.0. After fine-mapping studies, the results were replicated in 1,107 SSc patients and 2,747 controls from a(More)
INTRODUCTION SPARC is a matricellular protein, which, along with other extracellular matrix components including collagens, is commonly over-expressed in fibrotic diseases. The purpose of this study was to examine whether inhibition of SPARC can regulate collagen expression in vitro and in vivo, and subsequently attenuate fibrotic stimulation by bleomycin(More)
BACKGROUND Dry eye syndrome (DES) is a common ocular disorder occurring in general population. The purpose of this study is to evaluate the impact of DES on vision-related quality of life (QoL) in a non-clinic-based general population. METHODS This population-based cross-sectional study enrolled subjects older than 40 years, who took part in an(More)
In this paper, we study the problem of summarizing email conversations. We first build a sentence quotation graph that captures the conversation structure among emails. We adopt three cohesion measures: clue words, semantic similarity and cosine similarity as the weight of the edges. Second, we use two graph-based summarization approaches, Generalized(More)
Introduction • How best to convey large answer sets for queries? – Simple enumeration: accurate but not necessarily most useful – Summaries: not (necessarily) 100% accurate but can be more intuitive • Why is this problem interesting? – OLAP queries over multi-dimensional data typically produce data intensive answers
We present a wavelet multigrid preconditioner for the conjugate gradient method which gives an eecient solver for the linear system arising from a wavelet-Galerkin discretization of a Dirichlet boundary-value problem via a penalty//ctitious domain formulation. The pre-conditioner is chosen to be a wavelet-based multigrid method for solving the same elliptic(More)
The popularity of email has triggered researchers to look for ways to help users better organize the enormous amount of information stored in their email folders. One challenge that has not been studied extensively in text mining is the identification and reconstruction of hidden emails. A hidden email is an original email that has been quoted in at least(More)
Human leukocyte antigen DPB1 was reported to contain singly nucleotide polymorphisms conferring the strongest susceptibility to systemic sclerosis in Korean population. However, associations of specific DPB1 alleles with SSc vary in different ethnic populations. The aim of this study was to profile DPB1 alleles in Chinese population and to identify specific(More)