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— The presence of both multiple-access interference (MAI) and intersymbol interference (ISI) constitutes a major impediment to reliable communications in multipath code-division multiple-access (CDMA) channels. In this paper, an iterative receiver structure is proposed for decoding multiuser information data in a convolutionally coded asynchronous multipath(More)
We report here the purification of the third protein factor, Apaf-3, that participates in caspase-3 activation in vitro. Apaf-3 was identified as a member of the caspase family, caspase-9. Caspase-9 and Apaf-1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome c and dATP, an event that leads to(More)
The Biological General Repository for Interaction Datasets (BioGRID) is a public database that archives and disseminates genetic and protein interaction data from model organisms and humans (http://www.thebiogrid.org). BioGRID currently holds 347,966 interactions (170,162 genetic, 177,804 protein) curated from both high-throughput data sets and individual(More)
To meet the needs of wireless broadband access, the IEEE 802.16 protocol for wireless metropolitan networks (WirelessMAN) has been recently standardized. The medium access control (MAC) layer of the IEEE 802.16 has point-to-multipoint (PMP) mode and mesh mode. Previous works on the IEEE 802.16 have primarily focused on the PMP mode. In the mesh mode, all(More)
— The problem of blind demodulation of multiuser information symbols in a high-rate code-division multiple-access (CDMA) network in the presence of both multiple-access interference (MAI) and intersymbol interference (ISI) is considered. The dispersive CDMA channel is first cast into a multiple-input multiple-output (MIMO) signal model framework. By(More)
— The CSMA/CA protocols are designed under the assumption that all participant nodes would abide to the protocol rules. This is of particular importance in distributed protocols such as the IEEE 802.11 distributed coordinating function (DCF), in which nodes control their own backoff parameters. In this work, we propose a method to detect selfish misbehaving(More)
We report here the purification and cDNA cloning of Apaf-1, a novel 130 kd protein from HeLa cell cytosol that participates in the cytochrome c-dependent activation of caspase-3. The NH2-terminal 85 amino acids of Apaf-1 show 21% identity and 53% similarity to the NH2-terminal prodomain of the Caenorhabditis elegans caspase, CED-3. This is followed by 320(More)
We have identified and purified from HeLa cytosol a protein that induces DNA fragmentation in coincubated nuclei after it is activated by caspase-3. This protein, designated DNA Fragmentation Factor (DFF), is a heterodimer of 40 kDa and 45 kDa subunits. The amino acid sequence of the 45 kDa subunit, determined from its cDNA sequence, reveals it to be a(More)
A cell-free system based on cytosols of normally growing cells is established that reproduces aspects of the apoptotic program in vitro. The apoptotic program is initiated by addition of dATP. Fractionation of cytosol yielded a 15 kDa protein that is required for in vitro apoptosis. The absorption spectrum and protein sequence revealed that this protein is(More)