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Background Oxidative stress is considered to have a causative role in the development of central nervous system diseases, such as Alzheimer’s disease, Parkinson’s disease, tumor, etc. Curcumin, a… Continue Reading
A phytochemical investigation of a 70 % ethanol extract of the stem bark of Dysoxylum lukii has resulted in the isolation of eight new tirucallane-type triterpenoids, one new limonoid, and five known… Continue Reading
OBJECTIVE
Experimental and clinical studies have shown that obstructive jaundice results in increased intestinal permeability. The mechanisms implicated in this phenomenon remain obscure. Integrated… Continue Reading
The hepatitis C virus protein NS3 suppresses TNF-α–stimulated activation of NF-κB by targeting LUBAC
The transcription factor nuclear factor κB (NF-κB) is crucial for innate immune defense against viral infections, and its activation requires the ubiquitylation of upstream proteins, including the… Continue Reading
Objective: To investigate anti-cancer activity of the novel survivin siRNA Folate Receptor (FR)-targeted Polyethylene-Glycol Liposomes (PEG) liposomes in K562-bearing nude mice. Methods: The leukemia… Continue Reading
Autoimmune regulator (Aire), primarily expressed in medullary thymic epithelial cells (mTECs), maintains central immune tolerance through the clearance of self-reactive T cells. Aire can also be… Continue Reading
We have previously reported that a novel polysaccharide, MPSSS, from Lentinus edodes can reverse the function of myeloid immune suppressor cell-mediated T cell inhibition and improve the efficacy of… Continue Reading
Xi bao yu fen zi mian yi xue za zhi = Chinese…
Objective To investigate the effect of saikosaponin D (SSD) on the proliferation and transformation of human embryonic lung fibroblasts (HELFs) induced by transforming growth factor-beta 1 (TGF-β1)… Continue Reading
Correction for ‘A siRNA-induced peptide co-assembly system as a peptide-based siRNA nanocarrier for cancer therapy’ by Wenjun Li et al., Mater. Horiz., 2018, 5, 745–752.