Xiaodong Shi

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Helicobacter pylori (H. pylori) persistently colonizes the gastric mucosa despite a vigorous immune response. Vacuolating cytotoxin secreted by H. pylori has turned out to be a potent immunomodulatory toxin, but the signal transduction pathways involved has not been studied in macrophages. We observed in this study that vacA-deficient H. pylori induced(More)
Background The deprivation or abnormality of the molecular function of Wnt/b-catenin triggers the genesis and development of AD, and b-catenin is an important positive mediator in the Wnt/b-catenin signaling pathway. In our previous study, we found that Curcumin could inhibit the expression of b-catenin and prevent AD, but the mechanisms were not fully(More)
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