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Treatment of neuropathic pain with opioid analgesics remains controversial and a major concern is the risk of addiction. Here, we investigated this issue with spared nerve injury (SNI) model of neuropathic pain in rats and mice. SNI prevented conditioned place preference (CPP) induced by low dose (3.5mg/kg) of morphine (MOR), which was effective for(More)
We examined adaptations in nucleus accumbens (NAc) neurons in mouse and rat peripheral nerve injury models of neuropathic pain. Injury selectively increased excitability of NAc shell indirect pathway spiny projection neurons (iSPNs) and altered their synaptic connectivity. Moreover, injury-induced tactile allodynia was reversed by inhibiting and exacerbated(More)
Keywords: Land use/land cover change Driving forces System dynamics Scenario simulation Resources based city a b s t r a c t During the past decades, land use land cover change (LUCC) has taken place around most Chinese cities at unprecedented rates. During this process, many rural lands, such as forests and wetlands, have transformed to human settlements.(More)
Identifying the breeding habitat of red-crowned crane (Grus japonensis) is essential for the management and conservation of this rare species. In the current study, we built a habitat suitability index (HSI) model for the breeding red-crowned crane in wetlands of the Zhalong National Nature Reserve of the Songnen Plain, China. The assessing factors to(More)
This paper introduces the identification results of a discrete-time model of a laser welding process whose input is the reciprocal of the welding speed and output is the width of the weld pool. To model this nonlinear process, a Hammerstein model is used. A series of step response experiments have been conducted to obtain the experimental data. A method has(More)
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