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Load balancing in the cloud computing environment has an important impact on the performance. Good load balancing makes cloud computing more efficient and improves user satisfaction. This article introduces a better load balance model for the public cloud based on the cloud partitioning concept with a switch mechanism to choose different strategies for(More)
Sex steroids control cell movement and tissue organization; however, little is known of the involved mechanisms. This report describes the ongoing dynamic regulation by estrogen of the actin cytoskeleton and cell movement in human vascular endothelial cells that depends on rapid activation of the actin-regulatory protein moesin. Moesin activation is(More)
Limited information is available on the effects of progestins on breast cancer progression and metastasis. Cell migration and invasion are central for these processes, and require dynamic cytoskeletal and cell membrane rearrangements for cell motility to be enacted. We investigated the effects of progesterone (P), medroxyprogesterone acetate (MPA),(More)
Progesterone plays a role in breast cancer development and progression but the effects on breast cancer cell movement or invasion have not been fully explored. In this study, we investigate the actions of natural progesterone and of the synthetic progestin medroxyprogesterone acetate (MPA) on actin cytoskeleton remodeling and on breast cancer cell movement(More)
BACKGROUND Estrogen is an established enhancer of breast cancer development, but less is known on its effect on local progression or metastasis. We studied the effect of estrogen receptor recruitment on actin cytoskeleton remodeling and breast cancer cell movement and invasion. Moreover, we characterized the signaling steps through which these actions are(More)
The elevated expression of vascular endothelial growth factor C (VEGF-C) is correlated with clinical cervical cancer metastasis and patient survival, which is interpreted by VEGF-C functions to stimulate angiogenesis and lymphatic genesis. However, the direct impact of VEGF-C on cervical cancer cell motility remains largely unknown. In this study, we(More)
Ubiquitous access to sophisticated internet services from diverse end devices across heterogeneous networks requires the injection of additional functionality into the network to handle protocol conversion, data transcod-ing, and in general bridge disparate network portions. Several researchers have proposed infrastructures for injecting such functionality;(More)
While progesterone plays multiple roles in the process of breast development and differentiation, its role in breast cancer is less understood. We have shown previously that progestins stimulate breast cancer cell migration and invasion because of the activation of rapid signaling cascades leading to modifications in the actin cytoskeleton and cell membrane(More)
This paper describes an adaptive network infrastructure, Composable Adaptive Network Services (CANS), for bridging the bandwidth and resource gap between network services and mobile clients. CANS enables construction of service access paths augmented with 'impedance matching' components that handle operations such as caching, protocol conversion, and(More)