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(+/-)-Praeruptorin A enantiomers exert distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis.
Limonoids from the fruits of Aphanamixis polystachya (Meliaceae) and their biological activities.
Seven new prieurianin-type limonoids, aphapolynins C-I (1-7), and a new aphanamolide-type limonoid, aphanamolide B (8), along with seventeen known compounds, were isolated from the fruits of…
Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease.
Design, synthesis and biological evaluation of imine resveratrol derivatives as multi-targeted agents against Alzheimer's disease.
Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease.
Chisopanins A-K, 11 new protolimonoids from Chisocheton paniculatus and their anti-inflammatory activities.
Cytotoxic Rocaglate Derivatives from Leaves of Aglaia perviridis
Rocaglates are a series of structurally complex secondary metabolites with considerable cytotoxicity that have been isolated from plants of the Aglaia genus (Meliaceae) and their structures were elucidated based on a joint effort of spectroscopic methods and single-crystal X-ray diffraction.
Design, synthesis, and acetylcholinesterase inhibitory activity of novel coumarin analogues.
Multifunctional tacrine-flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease.