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(+/-)-Praeruptorin A enantiomers exert distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis.
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Limonoids from the fruits of Aphanamixis polystachya (Meliaceae) and their biological activities.
Seven new prieurianin-type limonoids, aphapolynins C-I (1-7), and a new aphanamolide-type limonoid, aphanamolide B (8), along with seventeen known compounds, were isolated from the fruits of…
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Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease.
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Design, synthesis and biological evaluation of imine resveratrol derivatives as multi-targeted agents against Alzheimer's disease.
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Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease.
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Chisopanins A-K, 11 new protolimonoids from Chisocheton paniculatus and their anti-inflammatory activities.
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Cytotoxic Rocaglate Derivatives from Leaves of Aglaia perviridis
TLDR
Rocaglates are a series of structurally complex secondary metabolites with considerable cytotoxicity that have been isolated from plants of the Aglaia genus (Meliaceae) and their structures were elucidated based on a joint effort of spectroscopic methods and single-crystal X-ray diffraction.
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Design, synthesis, and acetylcholinesterase inhibitory activity of novel coumarin analogues.
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Multifunctional tacrine-flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease.
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A novel aporphine alkaloid from Magnolia officinalis.
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