Xiaobin Gao

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Recruitment of bone marrow-derived myelomonocytic cells plays a fundamental role in tumor angiogenesis and metastasis. Placental growth factor (PlGF) is a potent cytokine that can attract myelomonocytic cells to the tumor. However, the underlying mechanism remains obscure. In this study, we demonstrate that tumor-derived PlGF activates NFAT1 via vascular(More)
High-intensity focused ultrasound (HIFU) is emerging as an effective therapeutic modality in both thermal ablations for solid tumor/cancer and soft-tissue fragmentation. Mechanical and thermal effects, which play an important role in the HIFU treatment simultaneously, are dependent on the operating parameters and may vary with the progress of therapy.(More)
We consider a sensor scheduling and remote estimation problem with one sensor and one estimator. At each time step, the sensor makes an observation on the state of a source, and then decides whether to transmit its observation to the estimator or not. The sensor is charged a cost for each transmission. The remote estimator generates a real-time estimate on(More)
This paper considers a sequential estimation and sensor scheduling problem with one sensor and one estimator. The sensor makes sequential observations about the state of an underlying memoryless stochastic process, and makes a decision as to whether or not to send this measurement to the estimator. The sensor and the estimator have the common objective of(More)
The blood-brain barrier (BBB) is partially disrupted in brain tumors. Despite the gaps in the BBB, there is an inadequate amount of pharmacological agents delivered into the brain. Thus, the low delivery efficiency renders many of these agents ineffective in treating brain cancer. In this report, we proposed an "autocatalytic" approach for increasing the(More)
In this paper, we propose two stochastic distributed algorithms for solving linear algebraic equations in the form of Ax = b among a network of m > 1 agents. Each agent knows only a subset of the rows of the partitioned matrix [A b]. Each agent recursively updates its estimate of a solution based on the messages received only from its neighbors. The(More)
PGRP (peptidoglycan recognition protein) is a conserved protein family that recognizes the peptidoglycan in bacterial cell wall and causes the activation of various innate immune responses. Previous studies have reported that PGRP-SCs in Drosophila dampen the activation of Immune Deficiency (Imd) pathway to microbial infection, and participate in the(More)
This paper establishes an explicit relationship between stability conditions for slowly time-varying linear systems and switched linear systems. The concept of total variation of a matrix-valued function is introduced to characterize the variation of the system matrix. Using this concept, a result generalizing existing stability conditions for slowly(More)