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AIM To investigate the possible effects of telmisartan and losartan on cardiac function in adriamycin (ADR)-induced heart failure in rats, and to explore the changes in plasma level of angiotensin-(1-7)[Ang-(1-7)] and myocardial expression of angiotensin II type 1/2 receptors (AT(1)R / AT(2)R) and Mas receptor caused by the two drugs. METHODS Male(More)
The ATP-binding cassette transporter A1 (ABCA1) R219K gene polymorphism has been suggested to lower the risk of coronary artery disease (CAD). However, research results remain debatable. Meta-analysis involving 2,730 CAD patients and 2,658 controls was performed to investigate the relationship between ABCA1 R219K gene polymorphism and CAD in Chinese(More)
The ratcheting deformation of articular cartilage can be produced due to the repeated accumulations of compressive strain . The aim of this study was to investigate the ratcheting behavior of articular cartilage under cyclic compression. A series of cyclic compressive tests with different stress amplitudes and stress rates were conducted for pig knee(More)
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