Xiao-xue Xu

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Cyclin-dependent kinase 10 (Cdk10) is a Cdc2-related kinase and plays an essential role in the progression from the G2 to M phase of the cell cycle. However, relative little is known about its expression pattern, clinical relevance, and biological function in hepatocellular carcinoma (HCC). In the present study, we investigated the mRNA and protein(More)
Pulmonary embolism (PE) is a common, lethal, ischemic disease. PE-induced endothelium injury plays a critical role in the pathophysiological consequences of PE. Endothelial progenitor cells (EPCs) can be mobilized from the bone marrow to enter circulation and play important roles in repair of damaged endothelium. However, it is not yet known if EPC(More)
Culture of hippocampal neurons in low-Mg(2+) medium (low-Mg(2+) neurons) results in induction of continuous seizure activity. However, the underlying mechanism of the contribution of low Mg(2+) to hyperexcitability of neurons has not been clarified. Our data, obtained using the patch-clamp technique, show that voltage-gated Na(+) channel (VGSC) activity,(More)
OBJECTIVE To determine whether tanycytes be able to support the regeneration of completely transected spinal cord in adult rats. METHODS Subcultured tanycytes was transplanted into completely T8 transected spinal cord using the untranslated completely transected rats as control. After transplantation the rubrospinal motor evoked potentials were recorded(More)
The water flea Daphnia are planktonic crustaceans commonly found in freshwater environment that can switch their reproduction mode from parthenogenesis to sexual reproduction to adapt to the external environment. As such, Daphnia are great model organisms to study the mechanism of reproductive switching, the underlying mechanism of reproduction and(More)
Guo F, Zhou PD, Gao QH, Gong J, Feng R, Xu XX, Liu SY, Hu HY, Zhao MM, Adam HC, Cai JQ, Hao LY. Low-Mg treatment increases sensitivity of voltage-gated Na channels to Ca /calmodulin-mediated modulation in cultured hippocampal neurons. Am J Physiol Cell Physiol 308: C594 –C605, 2015. First published February 4, 2015; doi:10.1152/ajpcell.00174.2014.— Culture(More)
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