Xiao-ming Feng

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AIM To investigate whether the transfer of the IL-37b gene, a newly identified inhibitor of both innate and adaptive immunity, could improve the therapeutic efficacy of mesenchumal stromal cells (MSCs) in inflammatory bowel disease (IBD). METHODS The expression of IL-37 in biopsied specimens of the patients with active ulcerative colitis (UC) was detected(More)
AIM IL-37b has shown anti-cancer activities in addition to its anti-inflammatory properties. In this study, we investigated the effects of IL-37b on breast carcinoma growth in mice and to determine the involvement of T cell activation in the effects. METHODS IL-37b gene was transferred into mouse breast carcinoma cell line 4T1 (4T1-IL37b cells), the(More)
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