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PURPOSE To investigate the influence of color vision on myopia development by testing refraction error and axial length of the eye for high school students with and without color vision deficiency (CVD). METHODS A school-based cross-sectional, cluster sample study was conducted to test the color vision and refractive error of 16,539 high school students.(More)
We investigated whether different monochromatic lights with similar luminance or identical light quantum number produce predictable changes in refractive state and eye growth in early eye development in guinea pigs. In experiment I, three groups of guinea pigs (two weeks of age, n=18 in each group) were reared for 12 weeks under LED lighting of 430 nm(More)
OBJECTIVE To investigate the surgical characteristics and clinical results of Epi-LASIK on high myopia. METHODS Epi-LASIK was performed with a rotational epikeratome, which features a blunt oscillating blade. Corneal epithelial separation was achieved mechanically without the use of alcohol. Laser ablation was performed with Zeiss Mel-80 excimer laser.(More)
PURPOSE Influence of longitudinal chromatic aberration (LCA) on emmetropization during early eye development has not been studied in primates. We investigated the effects of quasi-monochromatic lighting on refractive development and eye growth in rhesus monkeys. METHODS Infant rhesus monkeys were raised under one of three lighting conditions for 51 weeks:(More)
The human eye has ethnic difference, the existing typical eye models are based on western eyes. A generic eye model based on Chinese population is presented for the first time. The statistical analyzed ocular parameters based on measured data are used for the initial generic eye model, and the wavefront aberration data obtained at two different pupil(More)
BACKGROUND Transforming growth factor β (TGFβ) is one of the most important growth factors in the development of fibrosis and scarring on cornea. Smad7, an inhibitory Smad, can inhibit TGFβ signal transduction. In recent years, effects of lentiviral-mediated Smad7 on inhibition of fibrosis on some organs have been studied, while little is known about the(More)
BACKGROUND Haze or corneal subepithelial fibrosis is one of the common complications after refractive surgery procedures, such as photorefractive keratectomy (PRK), laser epithelial keratomileusis, and epipolis laser in situ keratomileusis, which would result in refractive regression, decreased visual quality, and corneal opacification. Haze directly(More)
OBJECTIVE To compare the corneal hysteresis (CH) and corneal resistance factor (CRF) measured with the Ocular Response Analyzer (ORA) in normal and keratoconic eyes. METHODS It was a case-control study. Random selected 96 normal eyes and 46 keratoconic eyes in the same period were included in this study. Normal eyes were divided into 2 groups: high(More)
AIM All-trans retinoic acid (RA) is the only extrinsic biochemical candidate known to date that could act as a growth controller, the aim of this study was to investigate the expression cellular retinoic acid binding proteins I (CRABP-I) and retinoic acid receptor-β (RAR-β) in retina of the guinea pig eyes with experimental myopia. METHODS Ninety guinea(More)
AIM To compare the clinical performance of two types of silicon hydrogel contact lenses used as bandage lenses after LASEK surgery. METHODS A prospective, double-masked study was conducted on 42 eyes of 21 patients who received binocular LASEK surgeries. The interocular difference in spherical equivalent power was less than -1.50D. Patients were randomly(More)