• Publications
  • Influence
Limb ischemic preconditioning attenuates apoptosis of pyramidal neurons in the CA1 hippocampus induced by cerebral ischemia-reperfusion in rats.
TLDR
It is suggested that LIP can inhibit hippocampal neuronal apoptosis induced by cerebral ischemia-reperfusion, which contributes to the protection against the delayed neuronal death inducedby cerebral ischemic insult. Expand
[Intrathecal injection of Sar9, Met(O2)11-substance P, neurokinin-1 receptor agonist, increases nitric oxide synthase expression and nitric oxide production in the rat spinal cord].
TLDR
It might be concluded that the release of SP resulted from nociceptive afferents increased NOS expression and NO production of the rat spinal cord. Expand
Modulatory action of endogenous and exogenous nitric oxide on survival of alveolar macrophages from normal and bleomycin-treated rats.
TLDR
It is concluded that NO can induce the apoptosis of BLM AMs and normal AMs; that Bcl-2 and Bax are implicated in NO-induced apoptotic ofnormal AMs, whereas they are not involved in that of BLM Ams, suggesting the differential molecular mechanisms underlying the NO- induced apoptosis; and that endogenous NO promotes proliferation of BLMAMs, which might be associated with down-regulation of Bax. Expand
Contributions of spinal d-amino acid oxidase to bone cancer pain
TLDR
The results provide the first evidence that spinal DAAO contributes to the development of morphine tolerance to analgesia and bone cancer pain accounting for 40–50 % pain status, probably via production of hydrogen peroxide leading to activation of astrocytes. Expand
Down-regulation of spinal D-amino acid oxidase expression blocks formalin-induced tonic pain.
TLDR
Results suggest that down-regulation of spinal DAAO expression and enzymatic activity leads to analgesia with its mechanism potentially related to activation of astrocytes in the spinal cord. Expand
Role of endogenous peroxynitrite in pulmonary injury and fibrosis induced by bleomycin A5 in rats.
TLDR
The therapeutic potential of AG for pulmonary injury and fibrosis was realized partly by reducing ONOO- formation. Expand
[Baicalin prevents the up-regulation of connective tissue growth factor in fibrotic lungs of rats].
TLDR
It is suggested that Bai could prevent the up-regulation of CTGF expression in fibrotic lungs of rats receiving BLM instillation, which might be one of the mechanisms underlying the preventive effect of Bai on pulmonary fibrosis. Expand
[Effects of alpha-methyl-(4-tetrazolyl-phenyl) glycine on the induction of hippocampal ischemic tolerance in the rat].
TLDR
The results indicate that MTPG blocks the induction of BIT induced by CIP, suggesting that mGluR2/3 participates in the induction of brain ischemic tolerance, and that CIP could protect pyramidal neurons against the isChemic insult. Expand
3,7‐Bis(2‐hydroxyethyl)icaritin, a potent inhibitor of phosphodiesterase‐5, prevents monocrotaline‐induced pulmonary arterial hypertension via NO/cGMP activation in rats
TLDR
ICT is more effective in preventing MCT‐induced PAH in rats via NO/cGMP activation compared with ICA and demonstrates a novel mechanism of the action of ICT that may have value in prevention of PAH. Expand
[Effect of nitric oxide synthase inhibitor L-NAME on the induction of brain ischemic tolerance in rats].
TLDR
The results showed that 10-min ischemic insult resulted in an increase in the histological grade and a decrease in pyramidal neuronal density, indicating a more serious tissue injury, and indicated that NO is involved in the induction of BIT in vivo. Expand
...
1
2
3
...