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Background-Endocardial (EE) and myocardial capillary vascular endothelial (myocap VE) cells have been shown to modulate the contractile characteristics of myocardium in a calcium-dependent manner. We evaluated the endothelial-myocardial interaction in the rat postinfarction myocardial infarction (MI) model and the effects of captopril. Methods and(More)
Endocardial and vascular myocardial capillary endothelium has been shown to modulate the contractile characteristics of myocardium by altering myofibrillar affinity for calcium. Although the release of endothelial-derived substances that modify myocardial contractility has been shown to be altered in certain physiologic and pathologic situations, until now(More)
Cardiac endothelin-1 (ET-1) levels and ET receptor expression are increased in congestive heart failure (CHF). In order to determine whether this results in increased responsiveness of ET-A or ET-B receptors to ET-1, we evaluated the contractile effects of ET-1 in isolated papillary muscles isolated from hearts of control rats and from rats 4 weeks post(More)
OBJECTIVE The aim of this study was to determine the expression patterns of Mena and Her-2 in breast cancer tissues and to explore their clinical significance and correlation with clinicopathological parameters. METHODS The expression of Mena and Her-2 was detected in 40 breast cancer tissues and 14 normal breast tissues by immunohistochemistry, and the(More)
Cardiac contractility and the ability of myocardium to respond to various stimuli have been shown to be age-related. Endocardial endothelium has been shown to modulate the performance of its adjacent myocardium, and it has been proven that these changes are reversible by increasing extracellular calcium. This study was designed to evaluate whether the(More)
OBJECTIVE To investigate the clinicopathologic features of glioneuronal tumor with neuropil-like island (GTNI). METHODS Four cases of intracranial and spinal GTNI, including three cases of WHO grade Ⅲ, and one case of WHO grade Ⅱ with grade Ⅲ recurrence. HE and immunohistochemical (IHC) staining were used for pathologic analysis. Fluorescence in situ(More)
During the course of our continuous surveillance of Gallid herpesvirus 2 (GaHV-2), 44 isolates were obtained from GaHV-2-positive chickens of different flocks in China from 2009 to 2013. The meq gene, considered as a major GaHV-2 oncogene, was sequenced and was found to contain an open reading frame of 1020 nucleotides encoding a 339 amino acid (aa)(More)
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