Achieving site selectivity in C-H functionalization reactions is a significant challenge, especially when the target C-H bond is distant from existing functional groups. Coordination of a functional group to a metal is often a key driving force and control element in many important reactions including asymmetric hydrogenation, epoxidation and lithiation.… (More)
9-Methylacridine was identified as a generally effective ligand to promote a Pd(II)-catalyzed C(sp(3))-H and C(sp(2))-H alkylation of simple amides with various alkyl iodides. This alkylation reaction was applied to the preparation of unnatural amino acids and geometrically controlled tri- and tetrasubstituted acrylic acids.
Currently in the flatness feedback control of hot strip mill it mainly adopts conventional PID controller, the parameters of which are often designed to a kind of situation and are invariable, so it is difficult to keep flatness well in hot tandem rolling. On the base of analyzing the shape generation theory and model prediction control theory, the flatness… (More)