Xiao-Tong Wang

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There is evidence that adenosine acting at A(2A) receptors (A(2A)R) can influence striatal plasticity and cognitive functions. We examined spatial working memory in wild-type (WT) and A(2A) receptor knock-out (KO) mice using two assessments: the eight arm radial maze and a repeated trial Morris water maze (MWM) paradigm. Compared to WT littermates, A(2A)R(More)
Studies with multiple sclerosis patients and animal models of experimental autoimmune encephalomyelitis (EAE) implicate adenosine and adenosine receptors in modulation of neuroinflammation and brain injury. Although the involvement of the A(1) receptor has been recently demonstrated, the role of the adenosine A(2A) receptor (A(2A)R) in development of EAE(More)
Phytochelatins chelate heavy metal ions to decrease their toxicity. The chelates are then transferred to, and stored in, the vacuole. Phytochelatin synthase (PCS), which is involved in phytochelatin synthesis, is thought to be a key enzyme for phytoremediation. In this study, a PCS gene encoding phytochelatin synthase was cloned from poplar (Populus(More)
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