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Epithelial-to-mesenchymal transition (EMT) is an important driver of tumor invasion and metastasis, which causes many cancer deaths. Cancer stem cells (CSC) that maintain and initiate tumors have also been implicated in invasion and metastasis, but whether EMT is an important contributor to CSC function is unclear. In this study, we investigated whether a(More)
The vast majority of travel takes place within cities. Recently, new data has become available which allows for the discovery of urban mobility patterns which differ from established results about long distance travel. Specifically, the latest evidence increasingly points to exponential trip length distributions, contrary to the scaling laws observed on(More)
OBJECTIVE Levofloxacin has been proposed to replace clarithromycin for Helicobacter pylori treatment. Seven- and 10-day fluoroquinolone triple therapies have generally failed to achieve cure rates of ≥90%, whereas 14-day therapy has achieved 95% success. The aim was to assess the efficacy and effect of fluoroquinolone resistance on 14-day(More)
OBJECTIVES Arsenic trioxide (As(2)O(3)) was found to induce apoptosis in certain types of cancer cells including acute promyelocytic leukemia, and recently in solid tumors. We have previously demonstrated that As(2)O(3) has a therapeutic effect on cervical cancer by apoptosis promotion in vitro and in vivo. Here we further our study on the role of arsenic(More)
In the past few years, more and more researchers have paid close attention to the emerging field of delay tolerant networks (DTNs), in which network often partitions and endto-end paths do not exist nearly all the time. To cope with these challenges, most routing protocols employ the “store-carryforward” strategy to transmit messages. However, the(More)
AIM The objective of this study was to establish the prevalence of dentine hypersensitivity (DH) in Chinese urban adults and the possible effects of smoking on DH. MATERIALS AND METHODS A total of 2640 subjects were distributed equally in 12 communities in Chengdu and Xian City, respectively, and of all age groups (10 years for an age group) including the(More)
Arsenite is an established human carcinogen, and arsenite-induced inflammation contributes to malignant transformation of cells, but the molecular mechanisms by which cancers are produced remain to be established. The present results showed that, evoked by arsenite, secretion of interleukin-6 (IL-6), a pro-inflammatory cytokine, led to the activation of(More)
BACKGROUND & AIMS We assessed the efficacy and safety of 4 bismuth-containing quadruple regimens as empiric therapies for Helicobacter pylori infections in patients who did not respond to previous treatment. METHODS We performed a prospective single-center study of 424 patients with H pylori infection that was not eradicated by previous therapies.(More)
As a significant factor in urban planning, traffic forecasting and prediction of epidemics, modeling patterns of human mobility draws intensive attention from researchers for decades. Power-law distribution and its variations are observed from quite a few real-world human mobility datasets such as the movements of banking notes, trackings of cell phone(More)
People often have the demand to decide where to wait for a taxi in order to save their time. In this paper, to address this problem, we employ the non-homogeneous Poisson process (NHPP) to model the behavior of vacant taxis. According to the statistics of the parking time of vacant taxis on the roads and the number of the vacant taxis leaving the roads in(More)