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The link between long noncoding RNAs and depression
TLDR
It is speculated lncRNA might get the capability to regulate MDD, because recently data showed that the expression level of the majority of lncRNAs demonstrated a clear tendency of upregulation, and the certain dysregulated miRNAs and lnc RNAs in the MDD have been proved to have a co‐synergism mechanism. Expand
Exosomes derived from PEDF modified adipose‐derived mesenchymal stem cells ameliorate cerebral ischemia‐reperfusion injury by regulation of autophagy and apoptosis
TLDR
PEDF plays a role in exosome‐mediated prevention of cerebral I/R injury by modulating apoptotic factors and promoting autophagy, and in vivo experiments confirmed that exosomes from PEDF‐modified ADSCs ameliorated cerebral I-R injury. Expand
Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model.
TLDR
Venlafaxine improved the expression of BDNF by influencing the PI3k/PKB/eNOS pathway and repressed the apoptosis of hippocampal neurons and effectively improved the behavioral abilities of depressed rats. Expand
Complement protein C5a enhances the β-amyloid-induced neuro-inflammatory response in microglia in Alzheimer's disease.
TLDR
The complement protein C 5a could exaggerate the Aβ-induced neuroinflammatory response in microglia, and C5aR may be a potential therapeutic tool for AD treatment. Expand
Factors influencing quality of life in Chinese patients with persistent somatoform pain disorder
TLDR
Pain, depression, and anxiety were significantly correlated with QoL of PSPD patients while age, pain, and depression were important factors influencing PCS and MCS. Expand
Efficacy of venlafaxine extended-release monotherapy for first-episode depression with painful physical symptoms
TLDR
Venlafaxine XR is possibly an effective and safe option in the treatment of depression and associated painful physical symptoms and response and remission rates for pain responders were significantly greater than that for pain nonresponders. Expand
Altered Neural Correlates of Emotion Associated Pain Processing in Persistent Somatoform Pain Disorder: An fMRI Study
TLDR
The current findings provide some insights into the underlying relationship between emotion and pain‐related brain activity in patients with PSPD, which is of both theoretical and clinical importance. Expand
Relationship between depression and blood cytokine levels in lung cancer patients.
TLDR
Serum levels of IL-10, IL-6, and TNF-α are associated with depression scoring in patients with lung cancer, and their correlation with the degree of depression was analyzed. Expand
Clinical evaluation of the efficacy and safety of tandospirone versus sertraline monotherapy for social anxiety disorder: a randomized open‐label trial
  • Xiao Huang, Chao Li, +5 authors J. Ji
  • Psychology, Medicine
  • Human psychopharmacology
  • 1 November 2013
TLDR
The aim of this study was to examine the efficacy and safety of tandospirone in treating adolescents with SAD. Expand
Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model.
TLDR
Venlafaxine improved the expression of BDNF through working on PI3k/PKB/eNOS pathway and repressed the apoptosis of hippocampal neurons. Expand
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