Xianming Wang

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Fourteen beta-elemene derivatives containing a piperazine, a morpholine, a tetrahydropyrrole, a thiophenylethylamine, or a cyclohexamine group were synthesized. The structures of these beta-elemene derivatives were characterized with IR, 1H NMR, MS, and elemental analyses. All these derivatives had an increased anti-proliferative activity in human cervix(More)
The aim of the present study was to observe the efficacy of neoadjuvant trastuzumab combined with docetaxel and carboplatin (TCH), and docetaxel, epirubicin and cyclophosphamide (TEC) chemotherapy in human epidermal growth factor receptor‐2 (HER-2)-overexpressing breast cancer. The total cohort of 64 cases of HER‐2‐overexpressing breast cancer patients was(More)
The expression and functions of microRNA (miR)-411 have been investigated in several types of cancer. However, until now, miR-411 in human breast cancer has not been examined. The present study investigated the expression, biological functions and molecular mechanisms of miR‑411 in human breast cancer, discussing whether it offers potential as a therapeutic(More)
BACKGROUND The aim of the study was to evaluate the clinical efficacy of superselective intra-arterial targeted neo-adjuvant chemotherapy in the treatment of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and human epidermal growth factor receptor 2 (HER2)-negative (triple-negative) breast cancer. PATIENTS AND METHODS.: A total of 47(More)
In this study, the essential factors governing the Z-shaped explosion limits of hydrogen-oxygen mixtures are studied using eigenvalue analysis. In particular, it is demonstrated that the wall destruction of H and HO2 is essential for the occurrence of the first and third limits, while that of O, OH, and H2O2 play secondary, quantitative roles for such(More)
Contrast patterns describe differences between two or more data sets or data classes; they have been proven to be useful for solving many kinds of problems, such as building accurate classifiers, defining clustering quality measures, and analyzing disease subtypes. This article investigates the mining of a new kind of contrast patterns, namely(More)
The implications and features of network public opinion are introduced, and the feasibility of using linkage analysis technology to analyze the evolution trends of network public opinion is discussed. The evolution process of network public opinion with time and information source quality evaluation are studied with the use of BUT Web crawler as a tool and(More)