Xianling Zhang

Learn More
AMP-activated protein kinase (AMPK) is an essential sensor of cellular energy status. Defects in the α2 catalytic subunit of AMPK (AMPKα1) are associated with metabolic syndrome. The current study investigated the role AMPKα1 in the pathogenesis of obesity and inflammation using male AMPKα1-deficent (AMPKα1(-/-)) mice and their wild-type (WT) littermates.(More)
OBJECTIVES Duodenal-jejunal bypass (DJB) surgery can induce the rapid and durable remission of diabetes. Recent studies indicate that ameliorated hepatic insulin resistance and improved insulin signaling might contribute to the diabetic control observed after DJB. Ras homolog enriched in brain (Rheb) is reported to have an important role in insulin pathway,(More)
AMP-activated protein kinase a1 protects against diet-induced insulin resistance and obesity. The authors have formally requested to retract the above-titled article, which was published in the December 2012 print issue of Diabetes. The authors cite concerns that Figures 2F, 4G, and 6G included misgrouping errors that were not identified before the time of(More)
  • 1