Xiangying Meng

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Sensor convergence on the mobile phone is spawning a broad base of new and interesting mobile applications. As applications grow in sophistication, raw sensor readings often require classification into more useful application-specific high-level data. For example, GPS readings can be classified as running, walking or biking. Unfortunately, traditional(More)
High-speed, locational, phone-to-phone (HLPP) games and apps constitute a provocative class of mobile apps that are currently unsupported on commodity mobile devices. This work looks at a key problem for enabling HLPP: a specific variant of the localization problem in which two phones estimate each other's relative positions in 3D space without(More)
Some neurons in the nervous system do not show repetitive firing for steady currents. For time-varying inputs, they fire once if the input rise is fast enough. This property of phasic firing is known as Type III excitability. Type III excitability has been observed in neurons in the auditory brainstem (MSO), which show strong phase-locking and accurate(More)
Transient potassium currents distinctively affect firing properties, particularly in regulating the latency before repetitive firing. Pyramidal cells of the dorsal cochlear nucleus (DCN) have two transient potassium currents, I(Kif) and I(Kis), fast and slowly inactivating, respectively, and they exhibit firing patterns with dramatically variable latencies.(More)
Loss of a sensory modality can lead to functional enhancement of the remaining senses. For example, short-term visual deprivations, or dark exposure (DE), can enhance neuronal responses in the auditory cortex to sounds. These enhancements encompass increased spiking rates and frequency selectivity as well as increased spiking reliability. Although we(More)
Subplate neurons (SPNs) form one of the earliest maturing circuits in the cerebral cortex and are crucial to cortical development. In addition to thalamic inputs, subsets of SPNs receive excitatory AMPAR-mediated inputs from the developing cortical plate in the second postnatal week. Functionally silent (non-AMPAR-mediated) excitatory synapses exist in(More)
Mesenchymal stem cells (MSCs) have been used for therapy of type 1 diabetes mellitus. However, the in vivo distribution and therapeutic effects of transplanted MSCs are not clarified well. Herein, we reported that CdSe/ZnS quantum dots-labeled MSCs were prepared for targeted fluorescence imaging and therapy of pancreas tissues in rat models with type 1(More)
BACKGROUND Everolimus, an inhibitor of the mammalian target of rapamycin, shows promising antitumor activity when combined with trastuzumab and chemotherapy for human epidermal growth factor receptor-2 (HER2)-positive breast cancer or when combined with endocrine agents for hormone receptor (HR)-positive tumors. However, data are limited regarding the(More)
Autism spectrum disorder (ASD) involves deficits in speech and sound processing. Cortical circuit changes during early development likely contribute to such deficits. Subplate neurons (SPNs) form the earliest cortical microcircuits and are required for normal development of thalamocortical and intracortical circuits. Prenatal valproic acid (VPA) increases(More)
Phasic neurons typically fire only for a fast-rising input, say at the onset of a step current, but not for steady or slow inputs, a property associated with type III excitability. Phasic neurons can show extraordinary temporal precision for phase locking and coincidence detection. Exemplars are found in the auditory brain stem where precise timing is used(More)