Learn More
Multidrug resistance (MDR) is a serious obstacle encountered in cancer treatment. In this study, we established an in vitro multiple drug resistant HepG2 cell line (HepG2/ADM), and characterized its MDR. This model was used to screen potential candidate chemosensitisers from over 200 purified naturally occurring compounds extracted from plants and animals.(More)
High-speed, locational, phone-to-phone (HLPP) games and apps constitute a provocative class of mobile apps that are currently unsupported on commodity mobile devices. This work looks at a key problem for enabling HLPP: a specific variant of the localization problem in which two phones estimate each other's relative positions in 3D space without(More)
Sensor convergence on the mobile phone is spawning a broad base of new and interesting mobile applications. As applications grow in sophistication, raw sensor readings often require classification into more useful application-specific high-level data. For example, GPS readings can be classified as running, walking or biking. Unfortunately, traditional(More)
In this report, we describe a simple and fast method for creating a murine myocardial infarction model and providing a useful and convenient tool for the research in ischemic heart disease. We established acute myocardial infarction in the Kunming-strain mouse within 2 minutes by ligating the left anterior descending coronary artery. The model was evaluated(More)
A normalized cDNA library was constructed from the adductor muscle of M. yessoensis and acquired 4595 high quality expressed sequence tags (ESTs). After clustering and assembly of the ESTs, 3061 unigenes containing 654 contigs and 2407 singletons were identified. The contig length ranged from 266 bp to 2364 bp and the average length of these contigs was 544(More)
OBJECTIVES Reference intervals for clinically important elements in infants and children are rarely reported, despite their importance for accurate clinical decision-making. The exploration of such reference intervals is essential. DESIGN AND METHODS Seven elements, including copper (Cu), zinc (Zn), calcium (Ca), magnesium (Mg), iron (Fe), lead (Pb), and(More)
Myostatin (MSTN) is a member of the transforming growth factor-beta superfamily which negatively regulates growth of muscle tissue. In this study, 103 cultivated Chlamys farreri individuals were screened for polymorphisms in the MSTN gene using PCR-single strand conformation polymorphism (PCR-SSCP) and DNA sequencing methods. Two mutations were found: A/G(More)
Some neurons in the nervous system do not show repetitive firing for steady currents. For time-varying inputs, they fire once if the input rise is fast enough. This property of phasic firing is known as Type III excitability. Type III excitability has been observed in neurons in the auditory brainstem (MSO), which show strong phase-locking and accurate(More)
Loss of a sensory modality can lead to functional enhancement of the remaining senses. For example, short-term visual deprivations, or dark exposure (DE), can enhance neuronal responses in the auditory cortex to sounds. These enhancements encompass increased spiking rates and frequency selectivity as well as increased spiking reliability. Although we(More)
To investigate the influence of the Morin transition on the photoelectrochemical (PEC) activity of hematite, electronic properties in different magnetic phases were studied on the basis of the first-principles calculations within the GGA+U approximation. The results show that the effective electron mass in the (0001) plane changes remarkably due to the(More)