Xiangyi Zheng

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OBJECTIVES To investigate the associations of prostate enlargement with obesity and hypertension in Chinese men. METHODS A total of 649 men from Zhejiang, China were invited to the Family Planning Station of Wenlin to undergo prostate volume measurement with transrectal ultrasonography. Benign prostatic enlargement (BPE) has been defined as a prostate(More)
Resveratrol, a naturally occurring polyphenolic antioxidant compound present in grapes and red wine, has been reported to hold various biochemical responses. In this preliminary study, we evaluate the chemopreventive potential of resveratrol against bladder cancer and its mechanism of action. Treatment of bladder cancer cells with resveratrol resulted in a(More)
Recent epidemiological studies have proposed that male circumcision reduces the relative risk of acquiring HIV-1. Here, we evaluated the density of Langerhans’ cell and degree of keratinization in the foreskins of Chinese preschool boys and adults. Sixty preschool boys and 20 healthy men without infectious history following male circumcisions were included.(More)
Increasing evidence has suggested that dysregulation of certain microRNAs (miRNAs) may contribute to human disease including carcinogenesis and tumor metastasis in human. miR-124-3p is down-regulated in various cancers, and modulates proliferation and aggressiveness of cancer cells. However, the roles of miR-124-3p in human bladder cancer are elusive. Thus,(More)
OBJECTIVE Previous epidemiologic studies demonstrated that obesity might associated with the risk of bladder cancer. However, many of the actual association findings remained conflicting. To better clarify and provide a comprehensive summary of the correlation between obesity and bladder cancer risk, we conducted a meta-analysis to summarize results of(More)
BACKGROUND Epidemiological studies of the association between nonsteroidal anti-inflammatory drug (NSAID) intake and the risk of prostate cancer still remain controversial. Therefore, we conducted a meta-analysis to evaluate the potential association between NSAID intake and prostate cancer risk. METHODS Eligible studies were retrieved by both(More)
As a main effector in the renin-angiotensin system, the angiotensin II plays a critical role in cell proliferation and angiogenesis. The change between angiotensin II and its precursor is conducted by the angiotensin-converting enzyme. The association between angiotensin-converting enzyme insertion/deletion polymorphism and the activity of(More)
Prostatic abscess involving the seminal vesicle is a rare disease due to the widespread use of broad-spectrum antibiotics in patients with lower urinary tract symptoms. With the elevated risk of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), a great emphasis on its pathogenicity in prostatic abscesses is required. To the best of(More)
It is increasingly clear that microRNAs play a crucial role in tumorigenesis. Recently, emerging evidence suggested that miR-26a is aberrantly expressed in tumor tissues. In our study, frequent down-regulation of miR-26a was observed in 10 human bladder cancer tissues. Forced expression of miR-26a in the bladder cancer cell line T24 inhibited cell(More)
OBJECTIVE Diabetes is associated with increased risk of cancer at several sites, but its association with risk of bladder cancer is still controversial. We examined this association by conducting a systematic review and meta-analysis of cohort studies. METHODS Studies were identified by searching PubMed, EMBASE, Scopus, Web of Science, Cochrane register,(More)