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Streptothricins (STs) are used commercially to treat bacterial and fungal diseases in agriculture. Mining of the sequenced microbial genomes uncovered two cryptic ST clusters from Streptomyces sp. C and Streptomyces sp. TP-A0356. The ST cluster from S. sp. TP-A0356 was verified by successful heterologous expression in Streptomyces coelicolor M145. Two new(More)
Streptomyces is studied intensively for its outstanding ability to produce bioactive secondary metabolites and for its complicated morphological differentiation process. A classical genetic manipulation system for Streptomyces has been developed and widely used in the community for a long time, using antibiotic resistance markers to select for(More)
Trajectories contain considerable routing information, and trajectory-based routing gains the attention of researchers recently. This paper argues the problem of searching time period Longest Frequent Path(TPLFP). The TPLFP, as one of the reasonable alternative Most Frequent Path (MFP), is close to MFP enough and maximizes the number of frequent route(More)
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