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OBJECTIVES The aim of this study was to test whether human leukocyte antigen (HLA) polymorphism contributes to the physical constitutions classified in Traditional Chinese Medicine (TCM). DESIGN Seven hundred six (706) individuals of the Han ethnic group inhabiting South China were classified into 7 TCM constitution groups, according to the criteria(More)
The majority of Miaos, Bouyeis, and Shuis are distributed in the Guizhou province of southwest China. They live within vast areas, while each ethnicity lives in individual concentrated communities in small areas. Their origin, migration, and relationship have long been interesting to anthropologists. In the present study, polymorphism of HLA-A, -B, and -C(More)
The complete genome sequence of infectious bursal disease virus (IBDV) YS07 strain with low mortality isolated from Guangdong province of China in 2007 was reported in this study. The genome sequences and deduced amino acid (aa) sequences of YS07 were compared with that of previously reported IBDV strains. Phylogenetic analyses based on the deduced aa(More)
Porcine reproductive and respiratory syndrome virus (PRRSV) is an enveloped virus, bearing severe economic consequences to the swine industry worldwide. Previous studies on enveloped viruses have shown that many incorporated cellular proteins associated with the virion's membranes that might play important roles in viral infectivity. In this study, we(More)
Infectious bronchitis virus (IBV) is the coronavirus of domestic chickens causing major economic losses to the poultry industry. Because of the complexity of the IBV life cycle and the small number of viral structural proteins, important virus-host relationships likely remain to be discovered. Toward this goal, we performed two-dimensional gel(More)
Newcastle disease virus (NDV) is an enveloped RNA virus, bearing severe economic losses to the poultry industry worldwide. Previous virion proteomic studies have shown that enveloped viruses carry multiple host cellular proteins both internally and externally during their life cycle. To address whether it also occurred during NDV infection, we performed a(More)
Synucleinopathy is characterized by abnormal accumulation of misfolded α-synuclein (α-Syn)-positive cytoplasmic inclusions and by neurodegeneration and cognitive impairments, but the pathogenesis mechanism of synucleinopathy remains to be defined. Using a transmission model of synucleinopathy by intracerebral injection of preformed A53T α-Syn fibrils, we(More)
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