Xiangao Huang

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Multiple myeloma (MM) remains incurable partly because no effective cell cycle–based therapy has been available to both control tumor cell proliferation and synergize with cytotoxic killing. PD 0332991 is an orally active small molecule that potently and specifically inhibits Cdk4 and Cdk6. It has been shown to induce rapid G 1 cell cycle arrest in primary(More)
Phosphatidylinositol-3-kinase (PI3K) signaling is constitutive in most human cancers. Selective inhibition of PI3Kδ (p110δ) by GS-1101 has emerged as a promising therapy in chronic lymphocytic leukemia and indolent lymphomas. In aggressive non-Hodgkin lymphomas such as mantle cell lymphoma (MCL), however, efficacy has been observed, but the extent and(More)
In this letter we assert that we have reconstructed the nonlinear filter function of LILI-128 stream cipher on IBM notebook PC using MATLAB. Our reconstruction need approximately 13 12 2 ~ 2 bits and the attack consumes 5825.016 sec (using tic and toc sentences of MATLAB) or 5825.016/3600=1.6181hours. We got the expression of the nonlinear filter function(More)
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