• Publications
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A Novel Coronavirus from Patients with Pneumonia in China, 2019
TLDR
Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily, which is the seventh member of the family of coronaviruses that infect humans. Expand
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
TLDR
The phylogenetic analysis suggests that bats might be the original host of this virus, an animal sold at the seafood market in Wuhan might represent an intermediate host facilitating the emergence of the virus in humans. Expand
Human infection with a novel avian-origin influenza A (H7N9) virus.
  • R. Gao, B. Cao, +42 authors Y. Shu
  • Biology, Medicine
  • The New England journal of medicine
  • 15 May 2013
TLDR
Novel reassortant H7N9 viruses were associated with severe and fatal respiratory disease in three patients, and all three patients died. Expand
Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study
TLDR
The first human infection with a novel reassortant avian influenza A H10N8 virus is reported, which was isolated from a patient from Nanchang City, China and caused human infection and could have been associated with the death of a patient. Expand
Biological features of novel avian influenza A (H7N9) virus
TLDR
It is shown that the emerging H7N9 avian influenza virus poses a potentially high risk to humans, and current seasonal vaccination could not provide protection. Expand
Human infection with a novel, highly pathogenic avian influenza A (H5N6) virus: Virological and clinical findings.
TLDR
A novel, highly pathogenic avian influenza H5n6 virus with a backbone of H5N1 virus acquired from the NA gene from the H6N6 virus has been identified and caused human infection resulting in severe respiratory disease. Expand
Genesis and Dissemination of Highly Pathogenic H5N6 Avian Influenza Viruses
TLDR
To investigate the genesis of the genetic diversity of these H5N6 viruses, 123 H5 or N6 environmental viruses sampled from live-poultry markets or farms from 2012 to 2015 in China were sequenced and indicated that three major reassortant viruses had been generated by two independent evolutionary pathways. Expand
Genetic Diversity of Avian Influenza A (H10N8) Virus in Live Poultry Markets and Its Association with Human Infections in China
TLDR
The notion that LPMs can act as both a gene pool for the generation of novel reassortants and a source for human infection is supported, and intensive surveillance and management should therefore be conducted. Expand
Development of Rapid Immunochromatographic Test for Hemagglutinin Antigen of H7 Subtype in Patients Infected with Novel Avian Influenza A (H7N9) Virus
TLDR
A rapid diagnostic test using anti-hemagglutinin (HA) monoclonal antibodies specifically targeting H7 in an immunochromatographic assay system that can specifically detect H7 HA antigen, facilitating rapid diagnosis for prevention and control of the on-going H7N9 epidemic. Expand
Genomic characterization of SARS-CoV-2 identified in a reemerging COVID-19 outbreak in Beijing's Xinfadi market in 2020
TLDR
There is an amino acid D614G mutation caused by nt23403 substitution in all six genomes of SARS-CoV-2, which may enhance the virus's infectivity in humans and help it become the leading strain of the virus to spread around the world today. Expand
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