Xiang Hui Gao

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Engineered TAL-effector nucleases (TALENs) and TALE-based constructs have become powerful tools for eukaryotic genome editing. Although many methods have been reported, it remains a challenge for the assembly of designer-based TALE repeats in a fast, precise and cost-effective manner. We present an ULtiMATE (USER-based Ligation Mediated Assembly of TAL(More)
BACKGROUND Dietary factors and history of smoking remain elusive in the pathogenesis of Parkinson's disease (PD). OBJECTIVE We investigated the association of environmental factors with PD in a rural population in China. METHODS Subjects were participants of a past nutritional intervention trial. Information on their characteristics was collected during(More)
  • X H Gao, S Alberverio, S M Fei, Z X Wang
  • 2005
The equivalence of multipartite quantum mixed states under local unitary transformations is studied. A criterion for the equivalence of non-degenerate mixed multipartite quantum states under local unitary transformations is presented. Quantum entangled states are playing fundmental roles in quantum information processing such as quantum computation, quantum(More)
OBJECTIVES In most reports, the prevalence of PD in mainland China is lower than in western populations. To estimate PD prevalence in China, we performed a cross-sectional study in a rural population in Linxian County, China. PRIMARY OUTCOMES Clinical diagnosis of PD. RESULTS Among the 16,488 participants examined, the overall age- and gender-adjusted(More)
Euroleon coreanus (Okamoto) is widely distributed in China, and the larval stage can be treated as traditional Chinese medicine. However, the host-bacterium relationship remains unexplored, as there is a lack of knowledge on the microbial community of ant lions. Hence, in the current study, we explored the microbial community of the larval ant lion E.(More)
Since extreme learning machine (ELM) was proposed, hundreds of studies have been conducted on this subject in various areas, from theoretical researches to practical applications. However, there are very few papers in the literature to reveal the reasons why in ELM classification the class with the highest output value is being chosen as the predicted class(More)
Cyclosporine A (CsA) is an immunosuppressant agent and is utilized as a second-line drug therapy for refrac-tory nephrotic syndrome (RNS). In general, the use of CsA is strictly controlled in patients with an estimated glomerular filtration rate (eGFR) <30-40 ml/min/1.73 m 2 , and little is known about the safety and efficacy of CsA treatment in patients(More)
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