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Cytotoxic Indole Alkaloids from Melodinus fusiformis and M. morsei
Abstract Aim To investigate antitumor indole alkaloids from the leaves and twigs of Melodinus fusiformis and M. morsei . Methods The indole alkaloids were isolated by column chromatography andExpand
Melodinines A-G, monoterpenoid indole alkaloids from Melodinus henryi.
Nineteen monoterpenoid indole alkaloids including seven new ones, melodinines A-G (1-7), were isolated from Melodinus henryi. The structures of the new compounds were elucidated using spectroscopicExpand
Melodinines M-U, cytotoxic alkaloids from Melodinus suaveolens.
TLDR
Nine new alkaloid structures, melodinines M-U (1-9), and 11 known alkaloids were isolated from Melodinus suaveolens by extensive NMR and mass spectroscopic analyses and comparison to known compounds. Expand
Sterols and terpenoids from Melia azedarach.
TLDR
Three new sterols including an unprecedented ring A-seco natural product (1) and five new terpenoids (4-8) were isolated from the bark of Melia azedarach, and the structure of 1 was confirmed by X-ray crystallography. Expand
New Antioxidant Phenolic Glycosides from Walsura yunnanensis
TLDR
Four new polyphenolic glycosides were isolated from the BuOH extract of the bark of Walsura yunnanenis C. Wu and displayed significant antioxidant activities, with IC50 values in the range of ca. Expand
Cytotoxic indole alkaloids from Tabernaemontana divaricata.
TLDR
Alkaloids 1 and 2 are the first vobasinyl-ibogan-type alkaloids possessing a six-membered ring via an ether linkage between C-17 and C-21, and show significant bioactivity against human cancer cell lines. Expand
Alkaloids from Melodinus yunnanensis.
TLDR
Meloyine I showed weak cytotoxic activity against four human cancer cell lines: MCF-7 breast cancer, SMMC-7721 hepatocellular carcinoma, HL-60 myeloid leukemia, and A-549 lung cancer. Expand
Dolabellane diterpenoids from Aglaia odorata.
TLDR
Compounds 1 and 5 showed weak cytotoxicity against the human myeloid leukemia HL-60, hepatocellular carcinoma SMMC-7721, and lung cancer A-549 cells. Expand
A cage-monoterpene indole alkaloid from Alstonia scholaris.
An unprecedented cage-like alkaloid, scholarisine A was isolated from the leaves of Alstonia scholaris and its structure determined on the basis of 1D and 2D NMR, FTIR, UV, and high-resolution massExpand
Cytotoxic indole alkaloids from Melodinus tenuicaudatus.
TLDR
Alkaloids 1, 3, and 4 and the known compound 11-methoxytabersonine (8) exhibited inhibitory effects, with IC(50) values comparable to those of cisplatin and vinorelbine. Expand
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