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Quercetin stimulates mitochondrial apoptosis dependent on activation of endoplasmic reticulum stress in hepatic stellate cells.

• Liwei He, Xianbang Hou, Fangtian Fan, Hongyan Wu
• Pharmaceutical biology
• 2016

CONTEXT Activation of hepatic stellate cells (HSCs) is a hallmark of liver fibrosis. Quercetin has benefits for liver fibrosis, but the mechanisms are unknown. OBJECTIVE We investigated the… (More)

Nuclear PKM2 expression, an independent risk factor for ER after curative resection of hepatocellular carcinoma.

• Fangtian Fan, Hongyan Wu, +4 authors Yin Lu
• Biomedicine & pharmacotherapy = Biomedecine…
• 2016

Surgical resection, providing a long-term survival of hepatocellular carcinoma (HCC) patients, is regarded as one of the standard curative treatments of HCC if the tumor is resectable. However, 50%… (More)

Resveratrol suppresses pulmonary tumor metastasis by inhibiting platelet-mediated angiogenic responses.

• Liwei He, Fangtian Fan, +5 authors Hongyan Wu
• The Journal of surgical research
• 2017

BACKGROUND To explore the impact of Resveratrol (RSV) on the angiogenic potential of activated platelets and to elucidate the underlying mechanism. METHODS Vascular endothelial growth factor… (More)

4(3H)-Quinazolone regulates innate immune signaling upon respiratory syncytial virus infection by moderately inhibiting the RIG-1 pathway in RAW264.7 cell.

• Liwei He, Fangtian Fan, +4 authors Yun Sun
• International immunopharmacology
• 2017

The root of Isatis indigotica, also known as Ban-Lan-Gen (BLG), is commonly used for prevention and early treatment of respiratory virus infection, but the underlying mechanisms of action remain… (More)

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