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This paper presents a data structure that reduces approximate nearest neighbor query times for image patches in large datasets. Previous work in texture synthesis has demonstrated real-time synthesis from small exemplar textures. However, high performance has proved elusive for modern patch-based optimization techniques which frequently use many exemplar(More)
This paper focuses on analyzing and predicting not-answered questions in Community based Question Answering (CQA) services, such as Yahoo! Answers. In CQA, users express their information needs by submitting questions and await answers from other users. One of the key problems of this pattern is that sometimes no one helps to give answers. In this paper, we(More)
The boom of product review websites, blogs and forums on the web has attracted many research efforts on opinion mining. Recently, there was a growing interest in the finer-grained opinion mining, which detects opinions on different review features as opposed to the whole review level. The researches on feature-level opinion mining mainly rely on identifying(More)
Domain adaptation is an important problem in named entity recognition (NER). NER classi-fiers usually lose accuracy in the domain transfer due to the different data distribution between the source and the target domains. The major reason for performance degrading is that each entity type often has lots of domain-specific term representations in the(More)
Activation of NF-κB and MAPK/activator protein 1 (AP-1) signaling pathways by receptor activator NF-κB ligand (RANKL) is essential for osteoclast activity. Targeting NF-κB and MAPK/AP-1 signaling to modulate osteoclast activity has been a promising strategy for osteoclast-related diseases. In this study we examined the effects of maslinic acid (MA), a(More)
Microfluidics is a convenient platform to study the influences of fluid shear stress on calcium dynamics. Fluidic shear stress has been proven to affect bone cell functions and remodelling. We have developed a microfluidic system which can generate four shear flows in one device as a means to study cytosolic calcium concentration ([Ca(2+)](c)) dynamics of(More)
Receptor activator of NF-κB ligand (RANKL) stimulation leads to the activation of mitogen-activated protein kinase (MAPK)/AP-1 and Ca2+–nuclear factor of activated T-cells cytoplasmic 1 (NFATc1) signaling pathways in osteoclastogenesis. Targeting these pathways has been an encouraging strategy for bone-related diseases, such as postmenopausal osteoporosis.(More)