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We used large-array optical recording procedures to examine maturation of regional neural activity within the ventral medullary surface (VMS) of anesthetized kittens during pharmacologically induced blood pressure elevation. Under sodium pentobarbital anesthesia, the VMS was exposed in 10, 20 and 30- to 45-day-old kittens and in adult cats. Arterial(More)
We examined ventral medullary surface activity using light reflectance procedures after blood pressure alterations induced by phenylephrine or sodium nitroprusside in 23 pentobarbital sodium-anesthetized cats. Images of reflected 660-nm light were collected and digitized at 1- to 3-s intervals after baseline and intravenous saline, 5-40 micrograms/kg(More)
Large-array optical recording procedures provide the potential to examine simultaneous activity of large numbers of neurons. We applied this technique to examine regional neuronal activation on the ventral medullary surface (VMS) of cats during hypoxic challenges. VMS was exposed through a ventral surgical approach in eight adult cats under pentobarbital(More)
BACKGROUND Testing for genetic risks of Factor V Leiden ( FVL ) in inflammatory bowel disease (IBD) patients with thromboembolism (TE) is common, but the safety and utility of such testing need review. AIM The aim of the present study was to investigate whether the FVL polymorphisms would be one inherited prothrombotic risk factor that could significantly(More)
We examined neuronal activation of the ventral medullary surface (VMS) during hypercapnic challenges using optical recording procedures. With a coherent imaging probe, we assessed reflected 700-nm light from 18 VMS sites in 11 spontaneously breathing adult cats and from the suprasylvian cortex in two cats. Video frames were acquired during a baseline(More)
On 10 New Zealand white rabbits immobilized with Flaxedil, the inhibitory effect of amygdaloid stimulation on the responses of medial geniculate body (MGB) neurons to tone bursts and the involved neurotransmitter mechanism were investigated with microiontophoresis technique. The results showed that application of GABA could cause a suppression of(More)
We used large-array optical recording procedures to examine maturation of regional neural activity within the ventral medullary surface (VMS) of anaesthetized kittens during graded hypercapnic and hypoxic challenges. The VMS was exposed through a ventral surgical approach in 10, 20, 30, and 45-day-old kittens and in adult cats under sodium pentobarbital(More)
Ethylcholine mustard aziridinium ion (AF64A), a neurotoxic choline analog, was injected (ICV) bilaterally (1.5 nmol/ventricle, n = 10) into male adult rats to induce a model of Alzheimer's disease (AD). One month later, using NADPH-diaphorase (NADPH-d) histochemistry followed by choline acetyltransferase (ChAT) immunocytochemistry (PAP) on the coronal(More)
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