Learn More
STUDY DESIGN A cross-sectional study in girls with adolescent idiopathic scoliosis (AIS) and healthy counterparts of similar age. OBJECTIVES To study the association of bone mass with anthropometric parameters, bone turnover, and calcium intake in 621 girls with AIS, aged 11-6-years, and compare the results with 300 healthy girls of similar age. SUMMARY(More)
The ensemble classifier plays a critical role in protein fold recognition. In this article, a novel hierarchical ensemble classifier named GAOEC (Genetic-Algorithm Optimized Ensemble Classifier) is presented and it can be constructed in the following steps. First, a novel optimized classifier named GAET-KNN (Genetic-Algorithm Evidence-Theoretic K Nearest(More)
BACKGROUND Low-intensity pulsed ultrasound has been demonstrated to be beneficial for accelerating fracture healing, delayed union, nonunion, and soft tissue repair. HYPOTHESIS Low-intensity pulsed ultrasound accelerates healing of bone-to-tendon junction repair by promoting osteogenesis and tissue remodeling at the healing junction. STUDY DESIGN(More)
Transforming growth factor-β (TGF-β) plays an important role in smooth muscle (SM) differentiation, but the downstream target genes regulating the differentiation process remain largely unknown. In this study, we identified olfactomedin 2 (Olfm2) as a novel regulator mediating SM differentiation. Olfm2 was induced during TGF-β-induced SM differentiation of(More)
STUDY DESIGN A cross-sectional study of the balance control in adolescents with idiopathic scoliosis. OBJECTIVE.: To investigate the relationship among somatosensory function, balance control, and adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA Balance control requires the contribution of somatosensory, visual, and vestibular inputs.(More)
We investigated the frequency and the clinical relevance of hepatitis B virus (HBV) pre-S mutations in Qidong, China. The results showed HBV pre-S mutants were detected in 48.4% (47/97) of patients with HBV infection. Both pre-S deletion and pre-S2 start codon mutations were more frequently found in HCC than in CH patients (51.1% vs. 18.0%, P < 0.01 and(More)
STUDY DESIGN A genetic association study of estrogen receptor-[alpha] gene (ESR1) with adolescent idiopathic scoliosis (AIS) in Chinese. OBJECTIVES To investigate whether: 1) PvuII and XbaI polymorphisms in ESR1 are predisposition factor for AIS and 2) these polymorphisms correlate with the severity of curvature in AIS. SUMMARY OF BACKGROUND DATA A(More)
Gene therapy has long been regarded a promising treatment for many diseases, whether acquired (such as AIDS or cancer) or inherited through a genetic disorder. A drug based on a nucleic acid, however, must be delivered to the interior of the target cell while surviving an array of biological defenses honed by evolution. Successful gene therapy is thus(More)
STUDY DESIGN Micro-computed tomography (CT) scanning to investigate three-dimensional microstructural properties of L4 vertebral bodies. OBJECTIVE To identify the regional variations in the three-dimensional microstructural properties of vertebral cancellous bones with respect to structural types for the prediction of related regional fracture risks. (More)