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AIM To explore the effect of hypothalamic arcuate nucleus (ARC) on the skeleton in rat. METHODS Newborn SD rats were injected by 10% MSG 4 g/kg hypodermically once every other day until the 10th day postnatally, meanwhile, the newborn rats in control group were given by equal volume of normal saline. After surviving for 200 days, 6 female rats in each… (More)