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The association between the signal transducer and activator of transcription 4 (STAT4) gene rs7574865 single nucleotide polymorphism and different autoimmune diseases remains controversial and ambiguous. We conducted this study to investigate whether combined evidence shows the association between STAT4 rs7574865 polymorphism and autoimmune diseases.(More)
AIMS Signal transducer and activator of transcription 4 (STAT4) gene encode a transcriptional factor that transmits signals induced by several key cytokines which play important roles in the development of autoimmune diseases. Recently, several single nucleotide polymorphisms (SNPs) in STAT4 gene have been reported to be significantly associated with(More)
We give the n! permutations of [n] = {1, 2,. .. , n} a cyclic order inspired by the chil-dren's game of Hot Potato. Our order is a transposition Gray code, meaning that consecutive permutations differ by a single transposition. Furthermore, each transposition is restricted in two ways: (1) It must transpose value n (the " hot potato "); (2) It must(More)
AIM To apply 3.0 magnetic resonance imaging (MRI) to study the effects of long-term, low dose hormone replacement therapy (HRT) on the brain parenchyma of postmenopausal women. METHODS A total of 155 postmenopausal healthy female medical staff members from Peking Union Medical College Hospital were enrolled. The HRT group was composed of 71 subjects who(More)
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