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  • Christophe Le Tourneau, Jean-Pierre Delord, +20 authors Xavier Paoletti
  • Medicine
  • The Lancet. Oncology
  • 2015 (First Publication: 1 October 2015)
  • BACKGROUND Molecularly targeted agents have been reported to have anti-tumour activity for patients whose tumours harbour the matching molecular alteration. These results have led to increasedExpand
  • Esma Saâda-Bouzid, Cécile Defaucheux, +11 authors Christophe Le Tourneau
  • Medicine
  • Annals of oncology : official journal of the…
  • 2017 (First Publication: 1 July 2017)
  • Background Pembrolizumab and nivolumab are immune checkpoint inhibitors targeting PD-1 that have recently been approved in pretreated recurrent and/or metastatic head and neck squamous cell carcinomaExpand
  • Sandra Rebouissou, Isabelle Bernard-Pierrot, +25 authors François Radvanyi
  • Biology, Medicine
  • Science Translational Medicine
  • 2014 (First Publication: 9 July 2014)
  • A subtype of aggressive human muscle-invasive bladder cancer expresses basal epithelial markers and is sensitive to EGFR inhibition in preclinical models. Bladder Cancer’s Basal Instincts Like mostExpand
  • Sophie Postel-Vinay, Laurence Collette, +14 authors J -C Soria
  • Medicine
  • European journal of cancer
  • 2014 (First Publication: 1 August 2014)
  • INTRODUCTION Traditional dose-limiting toxicity (DLT) definition, which uses grade (G) 3-4 toxicity data from cycle 1 (C1) only, may not be appropriate for molecularly targeted agents (MTAs) ofExpand
  • Marie-Geneviève Huisse, Sébastian Pease, +9 authors Sylvie Chollet-Martin
  • Medicine
  • Critical care medicine
  • 2008 (First Publication: 1 August 2008)
  • Objective:The mechanisms linking severe inflammation and coagulation during heatstroke are poorly understood. Here, we examined the roles of the tissue factor pathway, leukocyte activation, andExpand