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An unusual Michael addition of 3,3-dimethoxypropanenitrile to 2-aryl acrylates: a convenient route to 4-unsubstituted 5,6-dihydropyrido[2,3-d]pyrimidines.
- Xavier Berzosa, Xavier Bellatriu, J. Teixidó, J. Borrell
- Medicine, Chemistry
- The Journal of organic chemistry
- 15 January 2010
An unusual Michael addition between 2-aryl-substituted acrylates and 3,3-dimethoxypropanenitrile which leads, depending on the reaction temperature (60 or -78 degrees C, respectively), to a… Expand