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We reported earlier that CSPP-L, the larger isoform of the Centrosome/Spindle Pole associated Protein 1, is a ciliary protein required for primary cilia formation in hTERT-RPE1 cells. CSPP-L was found to localize to the basal body and the proximal and distal end of the primary cilium, and to be essential for recruitment of its interaction partner NPHP8(More)
5-Fluorouracil (5-Fu) is one of the most commonly used drugs to treat gastric cancer; however, drug-resistance in cancer cells reduces the efficacy of 5‑Fu. Celecoxib may be able to reduce resistance to 5‑Fu chemotherapy. The aim of the present study was to investigate the inhibitory effects of a combination of 5‑Fu and celecoxib on implanted gastric cancer(More)
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