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Prevalence and Psychosocial Correlates of Mental Health Outcomes Among Chinese College Students During the Coronavirus Disease (COVID-19) Pandemic
A significant proportion of young adults exhibit clinically relevant posttraumatic stress disorder (PTSD), anxious or depressive symptoms, but a larger portion of individuals showed to effectively cope with COVID-19 pandemic. Expand
Chemoselective Alteration of Fluorophore Scaffolds as a Strategy for the Development of Ratiometric Chemodosimeters.
This work provides a strategy to design ratiometric sensors that display dramatic spectral shifts by leveraging the chemoselective reactivity of novel functional groups inserted within fluorophore scaffolds. Expand
The 8-silyloxyquinoline scaffold as a versatile platform for the sensitive detection of aqueous fluoride.
This work provides a template for the design of fluoride sensors capable of reporting on relevant concentrations of fluoride in the laboratory and in the field using a straightforward test-strip-based assay format. Expand
Cue-reactivity in the ventral striatum characterizes heavy cannabis use, whereas reactivity in the dorsal striatum mediates dependent use
The present findings suggest that an incentive sensitization of the ventral striatal reward system may promote excessive drug use in humans, whereas adaptations in dorsal striatal systems engaged in habit formation may promote the transition to addictive use. Expand
Design and evaluation of a real-time activity probe for focal adhesion kinase.
- Jon R. Beck, X. Zhou, Garrett R. Casey, Cliff I. Stains
- Chemistry, Medicine
- Analytica chimica acta
- 15 October 2015
The design, synthesis and optimization of a direct activity sensor for FAK and its application to screening FAK inhibitors are described and the utility of this platform using a set of well-characterized small molecule kinase inhibitors is demonstrated. Expand
Putamen volume predicts real‐time fMRI neurofeedback learning success across paradigms and neurofeedback target regions
It is revealed that gray matter volume of the right putamen could predict neurofeedback learning success across the three data sets (n = 66 in total), which may reflect an important role of instrumental learning processes and brain structural variations in associated brain regions for successful acquisition of fMRI neurofeed back‐guided self‐regulation. Expand
Cue Reactivity in the Ventral Striatum Characterizes Heavy Cannabis Use, Whereas Reactivity in the Dorsal Striatum Mediates Dependent Use.
- X. Zhou, Kaeli Zimmermann, +8 authors B. Becker
- Biological psychiatry. Cognitive neuroscience and…
- 1 August 2019
The current findings suggest that exaggerated responses of the ventral striatal reward system may promote excessive drug use in humans, whereas adaptations in dorsal striatal systems engaged in habit formation may promote the transition to addictive use. Expand
Oxytocin Modulates the Intrinsic Dynamics Between Attention-Related Large-Scale Networks.
The findings suggest that OXT may facilitate efficient attention allocation by modulating the intrinsic functional dynamics between DN components and large-scale networks involved in external attentional demands (SN and DAN). Expand
Oxytocin Facilitates Self-Serving Rather Than Altruistic Tendencies in Competitive Social Interactions Via Orbitofrontal Cortex
- Xiaolei Xu, Congcong Liu, +6 authors K. Kendrick
- Medicine, Psychology
- The international journal of…
- 1 June 2019
The findings suggest that in the context of competing motivations for exhibiting altruistic or self-interest behavior, oxytocin enhanced self- interest and this was associated with greater activation in frontal reward areas. Expand
Common and Disorder-Specific Neurofunctional Markers of Dysregulated Empathic Reactivity in Major Depression and Generalized Anxiety Disorder
- Xiaolei Xu, J. Dai, +12 authors B. Becker
- Medicine, Psychology
- Psychotherapy and Psychosomatics
- 26 November 2019
A confirmatory dimensional approach was employed to examine associations between MDD and GAD symptom load, and personal distress with rdAI pain empathic reactivity and connecAnxiety disorders and depression are highly prevalent, debilitating, and commonly comorbid mental disorders. Expand