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Recent duplications dominate NBS-encoding gene expansion in two woody species
Most disease resistance genes in plants encode NBS-LRR proteins. However, in woody species, little is known about the evolutionary history of these genes. Here, we identified 459 and 330 respectiveExpand
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Wnt5a functions in planar cell polarity regulation in mice.
Planar cell polarity (PCP) refers to the polarization of cells within the plane of a cell sheet. A distinctive epithelial PCP in vertebrates is the uniform orientation of stereociliary bundles of theExpand
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Force spectroscopy of the leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction.
Interactions between leukocyte function-associated antigen-1 (LFA-1) with its cognate ligand, intercellular adhesion molecule-1 (ICAM-1) play a crucial role in leukocyte adhesion. Because the cellExpand
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Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway
The mammalian auditory sensory organ, the organ of Corti, consists of sensory hair cells with uniformly oriented stereocilia on the apical surfaces and has a distinct planar cell polarity (PCP)Expand
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Phosphorylation of Serine 256 Suppresses Transactivation by FKHR (FOXO1) by Multiple Mechanisms
FKHR is a member of the FOXO subfamily of Forkhead transcription factors, which are important targets for insulin and growth factor signaling. FKHR contains three predicted protein kinase BExpand
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Over‐expression of sly‐miR156a in tomato results in multiple vegetative and reproductive trait alterations and partial phenocopy of the sft mutant
Plant microRNAs (miRNAs) are vital components of the translation control system that regulates plant development and reproduction. The biological function of sly‐miR156 was investigated byExpand
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Transcriptional profiles of drought-responsive genes in modulating transcription signal transduction, and biochemical pathways in tomato
To unravel the molecular mechanisms of drought responses in tomato, gene expression profiles of two drought-tolerant lines identified from a population of Solanum pennellii introgression lines, andExpand
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Over-expression of microRNA169 confers enhanced drought tolerance to tomato
Plant miRNA regulates multiple developmental and physiological processes, including drought responses. We found that the accumulation of Sly-miR169 in tomato (Solanum lycopersicum) was induced byExpand
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Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor
Dissecting VWF's Thrombogenic Potential Von Willebrand factor (VWF) is secreted from cells in an ultralarge form (ULVWF) in response to thrombogenic stimuli. Shear forces expose a binding site forExpand
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Improving deep neural network acoustic models using generalized maxout networks
Recently, maxout networks have brought significant improvements to various speech recognition and computer vision tasks. In this paper we introduce two new types of generalized maxout units, which weExpand
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