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Mutations in SLC20A2 link familial idiopathic basal ganglia calcification with phosphate homeostasis
Familial idiopathic basal ganglia calcification (IBGC) is a genetic condition with a wide spectrum of neuropsychiatric symptoms, including parkinsonism and dementia. Here, we identified mutations inExpand
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Rett syndrome and beyond: recurrent spontaneous and familial MECP2 mutations at CpG hotspots.
Rett syndrome (RTT) is a neurodevelopmental disorder characterized by loss of acquired skills after a period of normal development in infant girls. The responsible gene, encoding methyl-CpG bindingExpand
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Predicting Stock Market Indicators Through Twitter “I hope it is not as bad as I fear”
This paper describes early work trying to predict stock market indicators such as Dow Jones, NASDAQ and S&P 500 by analyzing Twitter posts. We collected the twitter feeds for six months and got aExpand
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Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair
UV-sensitive syndrome (UVSS) is an autosomal recessive disorder characterized by photosensitivity and deficiency in transcription-coupled repair (TCR), a subpathway of nucleotide-excision repair thatExpand
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Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute
Ebola virus infection can cause severe hemorrhagic fever with a high mortality in humans. The outbreaks of Ebola viruses in 2014 represented the most serious Ebola epidemics in history and greatlyExpand
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Wide Damping Region for LCL-Type Grid-Connected Inverter With an Improved Capacitor-Current-Feedback Method
This paper has presented a stability analysis of a LCL-type grid-connected inverter in the discrete-time domain. It has been found that even though the system is stable when the resonance frequencyExpand
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CCR4-NOT Deadenylates mRNA Associated with RNA-Induced Silencing Complexes in Human Cells
ABSTRACT MicroRNAs (miRNAs) repress gene expression posttranscriptionally by inhibiting translation and by expediting deadenylation so as to trigger rapid mRNA decay. Their regulatory influence isExpand
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Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome.
Reciprocal interactions between the metabolic system and immune cells play pivotal roles in diverse inflammatory diseases, but the underlying mechanisms remain elusive. The activation of bileExpand
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Mutations in HOXD13 underlie syndactyly type V and a novel brachydactyly-syndactyly syndrome.
HOXD13, the homeobox-containing gene located at the most 5' end of the HOXD cluster, plays a critical role in limb development. It has been shown that mutations in human HOXD13 can give rise to limbExpand
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Atmospheric and room temperature plasma (ARTP) as a new powerful mutagenesis tool
Developing rapid and diverse microbial mutation tool is of importance to strain modification. In this review, a new mutagenesis method for microbial mutation breeding using the radio-frequencyExpand
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