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Elatoside C protects against hypoxia/reoxygenation-induced apoptosis in H9c2 cardiomyocytes through the reduction of endoplasmic reticulum stress partially depending on STAT3 activation
Endoplasmic reticulum (ER) stress-induced apoptosis has been suggested to contribute to myocardial ischemia–reperfusion (I/R) injury. Elatoside C is one of the major triterpenoid compounds isolated… Expand
Characterization of aromatic glycosides in the extracts of Trollius species by ultra high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass…
- Lizhen Wu, Xiao-po Zhang, X. Xu, Qing-xia Zheng, J. Yang, W. Ding
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 5 March 2013
Ultra high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry (UHPLC/ESI-Q-TOF MS/MS) was used to investigate the MS… Expand
Wedelolactone Regulates Lipid Metabolism and Improves Hepatic Steatosis Partly by AMPK Activation and Up-Regulation of Expression of PPARα/LPL and LDLR
Hyperlipidemia is considered one of the greatest risk factors of cardiovascular diseases. We investigated the anti-hyperlipidemic effect and the underlying mechanism of wedelolactone, a plant-derived… Expand
Percutaneous closure of postinfarct muscular ventricular septal defects: a multicenter study in China.
BACKGROUND Surgical repair is an effective method to treat ventricular septal defect (VSD) complicating acute myocardial infarction (AMI). However, the mortality rate remains high. This study was… Expand
Ephrin-B2/Fc promotes proliferation and migration, and suppresses apoptosis in human umbilical vein endothelial cells
Tumor growth and metastasis are angiogenesis dependent. Angiogenic growth involves endothelial cell proliferation, migration, and invasion. Ephrin-B2 is a ligand for Eph receptor tyrosine kinases and… Expand
Numerical simulation for the multi-point stretch forming process of sheet metal
Multi-point stretch forming (MPSF) is a flexible manufacturing technique to form large sheet panels of mild curvature. The traditional fixed shape-stretching die is replaced by a matrix of punch… Expand
Protective effects of total flavonoids from Clinopodium chinense (Benth.) O. Ktze on myocardial injury in vivo and in vitro via regulation of Akt/Nrf2/HO-1 pathway.
- H. Zhang, R. Chen, +4 authors X. Sun
- Chemistry, Medicine
- Phytomedicine : international journal of…
- 1 February 2018
BACKGROUND Clinopodium chinense (Benth.) O. Ktze is a traditional Chinese herbal medicine, which comprises the plant's total flavonoids. TFCC plays an important role in the treatment of… Expand
New phenylpropanoid derivatives from the fruits of Xanthium sibiricum and their anti-inflammatory activity.
The fruits of Xanthium sibiricum Patr yielded five phenylpropanoid derivatives, named as xanthiumnolics A-E (1-5). Their structures were elucidated by spectroscopic analysis and comparison with… Expand
Norcassane- and cassane-type furanoditerpenoids from the seeds of Caesalpinia sappan.
Three novel furanoditerpenoids, norcaesalpinin J (1) featuring an unusual 20-norcassane hydroperoxide and phangininoxys B (2) and C (3) possessing cassane hemiketal skeletons, were isolated from the… Expand
Novel dinorcassane- and cassane-type diterpenes from the seeds of Caesalpinia minax.
Two novel diterpenes, norcaesalpinin I (1) featuring an unusual ring C-contracted dinorcassane and caesalpinin U (2) possessing a highly oxygenated furanocassane skeleton were isolated from the seeds… Expand