• Publications
  • Influence
Dysbiosis Signature of Fecal Microbiota in Colorectal Cancer Patients
The human gut microbiota is a complex system that is essential to the health of the host. Increasing evidence suggests that the gut microbiota may play an important role in the pathogenesis ofExpand
  • 268
  • 22
Novel Plasmid and Its Variant Harboring both a blaNDM-1 Gene and Type IV Secretion System in Clinical Isolates of Acinetobacter lwoffii
  • Hongyan Hu, Y. Hu, +14 authors B. Zhu
  • Biology, Medicine
  • Antimicrobial Agents and Chemotherapy
  • 30 January 2012
ABSTRACT The spread of the blaNDM-1 gene is gaining worldwide attentions. This gene is usually carried by large plasmids and has been discovered in diverse bacteria since it was originally found inExpand
  • 106
  • 10
Lung-resident eosinophils represent a distinct regulatory eosinophil subset.
Increases in eosinophil numbers are associated with infection and allergic diseases, including asthma, but there is also evidence that eosinophils contribute to homeostatic immune processes. In mice,Expand
  • 154
  • 9
  • PDF
CXCR2 Promotes Ovarian Cancer Growth through Dysregulated Cell Cycle, Diminished Apoptosis, and Enhanced Angiogenesis
Purpose: Chemokine receptor CXCR2 is associated with malignancy in several cancer models; however, the mechanisms involved in CXCR2-mediated tumor growth remain elusive. Here, we investigated theExpand
  • 130
  • 9
  • PDF
QDMR: a quantitative method for identification of differentially methylated regions by entropy
DNA methylation plays critical roles in transcriptional regulation and chromatin remodeling. Differentially methylated regions (DMRs) have important implications for development, aging and diseases.Expand
  • 83
  • 8
  • PDF
Gavage of Fecal Samples From Patients With Colorectal Cancer Promotes Intestinal Carcinogenesis in Germ-Free and Conventional Mice.
BACKGROUND & AIMS Altered gut microbiota is implicated in development of colorectal cancer (CRC). Some intestinal bacteria have been reported to potentiate intestinal carcinogenesis by producingExpand
  • 164
  • 7
Integrated Laplacian‐based phase unwrapping and background phase removal for quantitative susceptibility mapping
TLDR
We present a method that simultaneously performs phase unwrapping and HARmonic (background) PhasE REmovaL using the LAplacian operator (HARPERELLA). Expand
  • 167
  • 6
Dysbiosis of Fungal Microbiota in the Intestinal Mucosa of Patients with Colorectal Adenomas
The fungal microbiota is an important component of the human gut microbiome and may be linked to gastrointestinal disease. In this study, the fungal microbiota of biopsy samples from adenomas andExpand
  • 68
  • 3
The antitumoral effect of Paris Saponin I associated with the induction of apoptosis through the mitochondrial pathway
Rhizoma Paridis, a traditional Chinese medicine, has shown promise in cancer prevention and therapy. In the present study, we isolated Paris Saponin I (PSI), an active component of Rhizoma paridis,Expand
  • 51
  • 3
  • PDF
Endostatin induces autophagy in endothelial cells by modulating Beclin 1 and β-catenin levels
Endostatin is a well‐characterized endogenous inhibitor of angiogenesis that affects cell proliferation and migration by inhibiting integrin and Wnt‐mediated signalling pathways. Here, we show thatExpand
  • 72
  • 3