Adaptor protein complex 2–mediated, clathrin‐dependent endocytosis, and related gene activities, are a prominent feature during maturation stage amelogenesis
Using real‐time PCR, it is shown that the expression of clathrin and adaptor protein subunits are upregulated in maturation stage rodent enamel organ cells, supporting the existence of a membrane‐bound receptor‐regulated pathway for the endocytosis of enamel matrix proteins.
3. Protein-protein interactions of the developing enamel matrix.
Iron Deposition and Ferritin Heavy Chain (Fth) Localization in Rodent Teeth
Iron was detected in ameloblasts of erupting third molars of 4-week old rats, suggesting iron plays a role in both incisor and molar development, and this is consistent with iron’s role in collagen synthesis.
The Amiloride-sensitive Epithelial Sodium Channel α-Subunit Is Transcriptionally Down-regulated in Rat Parotid Cells by the Extracellular Signal-regulated Protein Kinase Pathway*
- Mark D. Zentner, H. H. Lin, X. Wen, Kwang Jin Kim, D. Ann
- BiologyJournal of Biological Chemistry
- 13 November 1998
Pretreatment of cells with a specific inhibitor of the ERK kinase pathway, PD 98059, markedly abolished the down-regulation of α-ENaC expression, consistent with the hypothesis that the ERk kinase-signaling pathway is involved in TPA-mediated repression.
The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression.
The Sodium Bicarbonate Cotransporter (NBCe1) Is Essential for Normal Development of Mouse Dentition*
This study provides a mechanistic model to account for enamel abnormalities in certain patients with pRTA and shows for the first time that NBCe1 expression is required for the development of normal enamel.
Cellular uptake of amelogenin, and its localization to CD63, and Lamp1-positive vesicles
Analysis of molecular events of intercellular trafficking of an exogenous source of amelogenin and related this movement to the spatiotemporal expression of CD63 and Lamp1 using various cell lineages indicate a possible mechanism by which amelogenic peptides are removed from the extracellular matrix during enamel formation and maturation.
SLC26A Gene Family Participate in pH Regulation during Enamel Maturation
Evidence is presented that Sl c26a1, Slc26a6 and Slc 26a7 are novel participants in the extracellular transport of bicarbonate during enamel maturation, and that their functional roles may be achieved by forming interaction units with Cftr.
TFIP11 Interacts with mDEAH9, an RNA Helicase Involved in Spliceosome Disassembly
TFIP11 recruits mDEAH9 suggesting that these two proteins have similar biological activities to their yeast counterparts, based on amino-acid sequence similarities across species.
Identification of a novel nuclear localization signal and speckle-targeting sequence of tuftelin-interacting protein 11, a splicing factor involved in spliceosome disassembly.